FEATURE	DESCRIPTION
Pharmaceutical class	not communicated
Active substance (s)	for one capsule: caffeine (62.5 mg), paracetamol (400.0 mg), codeine (phosphate) hemihydrate (20.0 mg)
General medicine	no
Pharmaceutical form	capsule
Route (s) of administration	oral
Selling price	unregulated price
Social security reimbursement rate	0%
Laboratory (s)	Migralgine manufacturer (s)
Conditions of issue	available without prescription

Migralgine Dosage

RESERVED FOR ADULTS.

The recommended daily dose of paracetamol is approximately 60 mg / kg / day, divided into 4 or 6 divided doses, i.e. approximately 15 mg / kg every 6 hours or 10 mg / kg every 4 hours.

1 capsule, to be renewed if necessary after 4 hours, or possibly 2 capsules per dose in the event of severe pain, without exceeding 6 capsules per day.

However, in case of more intense pain, and on the advice of your doctor, the total dose may be increased up to 4 g per day.

However:

doses greater than 3 g of paracetamol per day require medical advice.
NEVER TAKE MORE THAN 4 GRAMS OF PARACETAMOL PER DAY (taking into account all drugs containing paracetamol in their formula).

Always respect an interval of at least 4 hours between the catches.

In the event of severe kidney disease (severe renal failure), the intakes should be 8 hours apart and the total dose should not exceed 6 capsules per day (3 g).

IF IN DOUBT, ASK YOUR DOCTOR OR PHARMACIST FOR ADVICE.

Migralgine Contraindications

Never take MIGRALGINE, capsule in the following cases:

Child under 15 years old.
Allergy to paracetamol and / or codeine, or to other constituents.
Severe liver disease.
Respiratory failure regardless of its importance.
Feeding with milk.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

How To Take Migralgine ?

Administration mode

Oral route.
The capsules are to be swallowed without opening them with a drink (eg water, milk, fruit juice).

Frequency of administration

Systematic catches prevent oscillations of pain or fever.
In adults, they must be spaced at least 4 hours apart.
In the event of serious kidney disease (severe renal failure), the catches should be spaced at least 8 hours apart.

Duration of the treatment

Do not use for a prolonged period without medical advice.

How To Store Migralgine ?

Keep this medication out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton. The expiration date refers to the last day of that month .

Store at a temperature not exceeding 30 ° C and protected from moisture.

Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

Migralgine Side Effects

Like all medicines, MIGRALGINE, capsule can cause side effects, although not everybody gets them.

RELATED TO THE PRESENCE OF PARACETAMOL

In rare cases, a rash or redness of the skin or an allergic reaction may occur, which may manifest as sudden swelling of the face and neck or sudden discomfort with a drop in blood pressure. You must stop treatment immediately , tell your doctor and never take medicines containing paracetamol again.
Exceptionally, biological changes requiring control of the blood test have been observed: abnormally low levels of certain white blood cells or certain blood cells such as platelets which may result in nosebleeds or gums. In this case, consult a doctor.

RELATED TO THE PRESENCE OF CODEINE

Possibility of :

feeling drowsy, euphoria, mood swings,
narrowing of the pupil, difficulty urinating,
constipation, nausea, vomiting,
drowsiness, dizziness,
hypersensitivity reactions (pruritus, hives and, in rare cases, extensive rash),
respiratory problems,
abdominal pain especially in cholecystectomized patients (without gallbladder).

RELATED TO THE PRESENCE OF CAFEINE

This medicine may cause you to feel excited, sleepless, and heart beat.

If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.

Keep out of the reach and sight of children.

Migralgine Interactions

This drug should be avoided with morphine agonist-antagonists (buprenorphine, nalbuphine, pentazocine), with alcoholic beverages or drugs containing alcohol, with naltrexone or with enoxacin (antibiotic).

Report that you are taking this medicine if your doctor prescribes a test for the level of uric acid in the blood.

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

The attention of machine users and vehicle drivers is drawn to the risks of drowsiness associated with the use of this medication.
This phenomenon diminishes after several takes.
This phenomenon is accentuated by the consumption of alcoholic beverages.

Warnings and Precautions

Special warnings

Please note, this medication is not a treatment for migraine or headache.

This medicine contains paracetamol. In case of overdose or mistakenly taking too high a dose, consult your doctor immediately.
Depending on your individual ability to process codeine, you may show signs of overdose even if you are taking this medicine at the dose recommended by your doctor. If symptoms such as dizziness, drowsiness, abdominal pain, and difficulty breathing appear, tell your doctor immediately.
This medicine contains paracetamol, codeine and caffeine. Other medicines contain it. Do not combine them so as not to exceed the maximum recommended doses.
Do not use this medication for a long time because of the risk of dependence.
Some pain may not be relieved by this medicine, ask your doctor for advice.
This medicine contains lactose. Its use is not recommended in patients with lactose intolerance (a rare hereditary disease).

Precautions for use

If the pain persists for more than 5 days or the fever for more than 3 days, or in the event of insufficient efficacy or the occurrence of any other sign, do not continue treatment without the advice of your doctor.
Before taking this medicine, it is necessary to consult your doctor in case of severe kidney or liver disease.
Due to the presence of caffeine, this medication can cause insomnia; consequently, catches at the end of the day should be avoided.
This medication is not recommended with morphine agonist-antagonists (buprenorphine, nalbuphine, pentazocine), the intake of alcoholic beverages or drugs containing alcohol, naltrexone or enoxacin (antibiotic).
IF IN DOUBT, DO NOT HESITATE TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

This medicine will only be used during pregnancy on the advice of your doctor.
If you discover that you are pregnant during treatment, consult your doctor as only he can judge the need for continued treatment.

Feeding with milk

This medicine passes into breast milk.
Never take this medicine without medical advice if you are breast-feeding. This is because you could expose your baby to serious side effects.
Any manifestation of undesirable effect in you (very strong drowsiness, confusion or respiratory depression) or in your child (drowsiness, difficulty in sucking, breathing difficulties) requires prompt stopping your treatment with codeine and consultation with your doctor.
In the event of breast-feeding, apart from a one-off intake on prescription from your doctor, this medication is contraindicated.
In general, during pregnancy or breastfeeding, always seek the advice of your doctor or pharmacist before using any medication.

What happens if I overdose from Migralgine ?

Immediately consult your doctor or pharmacist.

What should I do if I miss a dose?

Not applicable.
Not applicable.
Not applicable.
Not applicable.

What happens if you stop taking Migralgine ?

Not applicable.
Not applicable.
Not applicable.
Not applicable.

What is Forms and Composition ?

COMPOSITION

Active substances

Paracetamol: 400.0 mg
Caffeine: 62.5 mg
Codeine phosphate hemihydrate: 20.0 mg
For a capsule.

Other components

Colloidal anhydrous silica, lactose monohydrate, glycerol monostearate.
Composition of the capsule shell: gelatin, indigotine (E 132), quinoline yellow (E 104), titanium dioxide (E 171).

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.