100 mg sachet: This presentation is reserved for children from 6 to 20 kg(approximately 3 months to 7 years).
Sachet 150 mg: This presentation is reserved for children from 8 to 30 kg(about 6 months to 11 years).
200 mg sachet: This presentation is reserved for children from 11 to 25 kg(approximately 18 months to 10 years).
300 mg sachet: This presentation is reserved for children from 16 to 48 kg(approximately 4 to 15 years old).

Suppository:

Suppository 100 mg: This presentation is reserved for infants weighing 3 to 8 kg(approximately from birth to 9 months).
Suppository 150 mg: This presentation is for infants weighing 8 to 12 kg(approximately 6 to 24 months).
Suppository 200 mg: This presentation is reserved for children weighing 12 to 16 kg(about 2 years to 5 years).
Suppository 300 mg: This presentation is reserved for children weighing 15 to 24 kg(about 4 years to 9 years).

doliprane dosage in english

Administration mode

Oral way.

The capsules are swallowed as is with a drink (eg water, milk, fruit juice).
Capsule taking is contraindicated in children under 6 years of age because it can lead to a wrong course. Use another form.

Dosage

This presentation is reserved for adults and children from 27 kg (approximately from 8 years old).
In children, it is imperative to respect the dosages defined according to the weight of the childand therefore to choose a suitable presentation. Approximate ages by weight are given for information.
The recommended daily dose of paracetamol is approximately 60 mg / kg / day, to be divided into 4 or 6 doses, approximately 15 mg / kg every 6 hours or 10 mg / kg every 4 hours.
For children weighing 27 to 40 kg (approximately 8 to 13 years), the dosage is 1 capsule 500 mg per dose, to be renewed if necessary after 6 hours, without exceeding 4 capsules per day.
For children weighing 41 to 50 kg (approximately 12 to 15 years), the dosage is 1 capsule 500 mg per dose, to be renewed if necessary after 4 hours, without exceeding 6 capsules per day.
For adults and children weighing more than 50 kg (from about 15 years old);
The usual unit dosage is 1 to 2 capsules at 500 mg per dose, to be renewed if necessary after a minimum of 4 hours.
It is generally not necessary to exceed 3 g of paracetamol per day, or 6 capsules per day. However, in case of more intense pain, the maximum dosage can be increased up to 4 g per day, or 8 capsules per day.
Always observe a 4 hour interval between shots.

Maximum recommended doses : see section Warnings and precautions for use .

Frequency of administration

Systematic catches prevent pain or fever oscillations:

In children, they should be regularly spaced, including at night , preferably 6 hours , and at least 4 hours.
In adults, they must be spaced at least 4 hours apart.

Renal failure

In severe renal impairment (creatinine clearance <30 ml / min), the interval between two doses should be increased to at least 8 hours .
The dose of paracetamol should not exceed 3 g per day, ie 6 capsules.
The lowest effective daily dose should be considered, not to exceed 60 mg / kg / day (not to exceed 3 g / day) in the following situations:

Adults under 50 kg
Mild to moderate hepatocellular insufficiency
Chronic alcoholism
Chronic malnutrition
Dehydration

Contraindications

Paracetamol hypersensitivity
Severe hepatocellular impairment
Child before 6 years old
Alcohol consumption

Hypersensitivity to the active substance or to any of the excipients listed in section composition.

Severe hepatocellular failure.

Child less than 6 years old, because of the risk of wrongdoing.

How it works Doliprane?

OTHER Analgesics and Antipyretics -ANILIDES , ATC Code: N02BE01 . N: Central nervous system .

Paracetamol has a central and peripheral mechanism of action.

Doliprane Side Effects

Few cases of hypersensitivity reactions such as anaphylactic shock, angioedema, erythema, urticaria, skin rash have been reported.
Their occurrence requires the definitive discontinuation of this drug and related drugs.
Very exceptional cases of thrombocytopenia, leukopenia and neutropenia have been reported.

Doliprane Interactions

Symptomatic treatment of mild to moderate pain and / or febrile conditions.
Powder for oral solution:

100 mg sachet: This presentation is reserved for children from 6 to 20 kg(approximately 3 months to 7 years).
Sachet 150 mg: This presentation is reserved for children from 8 to 30 kg (about 6 months to 11 years).
200 mg sachet: This presentation is reserved for children from 11 to 25 kg (approximately 18 months to 10 years).
300 mg sachet: This presentation is reserved for children from 16 to 48 kg (approximately 4 to 15 years old).

Suppository:

Suppository 100 mg: This presentation is reserved for infants weighing 3 to 8 kg (approximately from birth to 9 months).
Suppository 150 mg: This presentation is for infants weighing 8 to 12 kg(approximately 6 to 24 months).
Suppository 200 mg: This presentation is reserved for children weighing 12 to 16 kg (about 2 years to 5 years).
Suppository 300 mg: This presentation is reserved for children weighing 15 to 24 kg (about 4 years to 9 years).

Doliprane Warnings and Precautions

Doliprane Warnings

To avoid a risk of overdose,
To check the absence of paracetamol in the composition of other medicinal products
Respect the maximum recommended doses

Maximum recommended doses :

In children under 40 kg , the total dose of paracetamol should not exceed 80 mg / kg / day (see section Overdose ).
In children between 41 and 50 kg , the total dose of paracetamol should not exceed 3 g per day (see section Overdose ).
In adults and children over 50 kg , the total dose of PARACETAMOL SHOULD NOT EXCEED 4 GRAMS PER DAY .
The tablet or capsule is contraindicated in children under 6 years of age because it can lead to a miscarriage.

Precautions for use

In a child treated with 60 mg / kg / day paracetamol, the combination of another antipyretic is justified only in case of ineffectiveness.
Paracetamol should be used with caution in case of:

weight <50kg
mild to moderate hepatocellular insufficiency
severe renal insufficiency (creatinine clearance £ 30ml / min (see sections Posology and method of administration and Pharmacokinetic properties ),
chronic alcoholism,
chronic malnutrition (low liver glutathione reserves),
Dehydration (see section Dosage and method of administration )

If acute viral hepatitis is found, treatment should be discontinued

Drive and use machines

Not applicable.

Doliprane and PREGNANCY / BREAST FEEDING / FERTILITY

doliprane during pregnancy

Studies in animals have not shown any teratogenic or foetotoxic effect of paracetamol.
Clinically, the results of epidemiological studies seem to exclude a particular malformative or fetotoxic effect of paracetamol.
As a result, paracetamol, under normal conditions of use, may be prescribed throughout pregnancy.

feeding

At therapeutic doses, administration of this drug is possible during breastfeeding.

What happens if I overdose from Doliprane ?

The risk of severe intoxication may be particularly high in the elderly, in young children, in patients with liver injury, in case of chronic alcoholism, in patients suffering from chronic malnutrition.
In these cases, intoxication can be fatal.

sYMPTOMS

Nausea, vomiting, anorexia, pallor, abdominal pain usually appear in the first 24 hours.
Overdose, starting with 10 g of paracetamol in a single dose in adults and 150 mg / kg of body weight in a single dose in children, causes hepatic cytolysis which may result in complete and irreversible necrosis Hepatocellular insufficiency, metabolic acidosis, encephalopathy that can lead to coma and death.
At the same time, there is an increase in hepatic transaminases, lactic dehydrogenase, bilirubin and a decrease in the prothrombin level that may occur 12 to 48 hours after ingestion.

Emergency driving

Immediate transfer to hospital.
Collect a tube of blood to do the initial plasma paracetamol test.
Rapid evacuation of the ingested product by gastric lavage.
The treatment of overdose typically comprises the administration as early as possible of the antidote N-acetylcysteine IV or oral route if possible before the tenth hour.
Symptomatic treatment.

What is Forms and Composition?

Doliprane powder for oral solution:

Powder for oral solution at 100, 150, 200 and 300 mg: sachets-dose, boxes of 12.
Doliprane suppository: Suppository breakable 100 mg: Box of 10, under blister packs.
Suppositories at 150, 200 and 300 mg: Boxes of 10, under blister packs.

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

It treats possible side effects and drug interactions that require attention and its effect on continuous use.
The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.

Paracetamol