KENALCOL Uses, Dosage, Side Effects, Precautions & Warnings

KENALCOL, solution for skin application
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Generic drug of the Therapeutic class: Dermatology
Active ingredients: Triamcinolone , Salicylic acid , Benzalkonium chloride

Medicinal product withdrawn from the market on 04/01/2008

what is KENALCOL medication used for and indication?

Corticosteroid-sensitive dermatoses with a keratotic or squamous component:

  • lichenification,
  •  psoriasis (excluding large-plaque psoriasis),
  • neurrodermatitis,
  •  lichen planus,
  • palmoplantar keratoderma.

KENALCOL Dosage

  • Treatment should be limited to 2 applications per day for 2 weeks then 1 time per day.
  • The duration of treatment will not exceed 4 weeks.
  • On average, 1 to 2 ml per day, or 10 to 20 sprays.
  • Do not exceed 3 ml per day, or 30 sprays.
  • An increase in the number of daily applications may worsen the side effects without improving the therapeutic effects.
  • The treatment of large surfaces requires monitoring of the number of vials used.

KENALCOL Contraindications

  • Hypersensitivity to any of the products contained in the preparation, in particular to salicylates or to a related substance.
  •  Primary bacterial, viral, fungal or parasitic infections.
  • Ulcerated lesions.
  • Acne.
  • Rosacea.
  • Application to the eyelids (risk of glaucoma).
  • Application on the mucous membranes.
  • Do not apply to the breasts during breastfeeding, because of the risk of ingestion of the product by the newborn.

How To Take KENALCOL ?

Method of administration :

  • Place the tip of the spray bottle approximately 5 cm from the lesions to be treated.
  • Certain skin conditions make gradual cessation desirable. It can be obtained by reducing the frequency of applications and / or by using a less strong or less dosed corticosteroid.

how does KENALCOL work?

ASSOCIATION OF A DERMOCORTICOIDE OF MODERATE ACTIVITY, OF A KERATOLYTIC AND OF AN ANTISEPTIC.

(D: dermatology).

  • Topical corticosteroids are classified into 4 activity levels according to skin vasoconstriction tests: very strong, strong, moderate, weak activity.
  • Kenalcol, solution for skin application is a combination of a corticosteroid of moderate activity, a keratolytic and an antiseptic, benzalkonium chloride, of the quaternary ammonium class.
  • Triamcinolone acetonide is the essential active substance.
  • Active on certain inflammatory processes (for example: contact hypersensitivity) and the pruritic effect which is linked to them.

Vasoconstrictor.

  • By adding salicylic acid, the stratum corneum is more permeable to the corticosteroid. At the same time, the reservoir function of the stratum corneum decreases and higher corticosteroid concentrations are found in the dermis than with corticosteroid alone.

KENALCOL Side Effects

Redness, burning sensation after application.

Due to the presence of a corticosteroid :

  • The prolonged use of corticosteroids of moderate activity can cause skin atrophy, telangiectasias (to be feared particularly on the face), stretch marks (at the root of the limbs in particular, and occurring more readily in adolescents), ecchymotic purpura secondary to atrophy, skin fragility.
  • On the face, corticosteroids can create perioral dermatitis or worsen rosacea (see contraindications, warnings and precautions for use).
  • A delay in healing of sluggish wounds, bedsores, leg ulcers may be observed (see contraindications).
  • Possibility of systemic effects (see warnings and precautions for use: cushingoid syndrome, growth retardation, acute adrenal insufficiency).
  • Acneiform or pustular eruptions, hypertrichosis, depigmentations have been reported.
  • Secondary infections, particularly under an occlusive dressing or in the folds, and allergic contact dermatoses have also been reported during the use of local corticosteroids.

KENALCOL Interactions

  • Systemic intake of salicylates and topical application containing salicylic acid should be avoided while using this medication.
  • Not applicable.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

WARNINGS

  • Prolonged use on the face of corticosteroids of very strong, strong or moderate activity exposes the occurrence of corticosteroid-induced dermatitis and, paradoxically, corticosteroid, with rebound after each stop. A gradual weaning, particularly difficult, is then necessary.
  • Due to the passage of the corticosteroid into the systemic circulation, treatment over large areas or under occlusion may cause the systemic effects of systemic corticosteroid therapy, particularly in infants and toddlers. They consist of a cushingoid syndrome and a slowing of growth. These accidents disappear when treatment is stopped, but abrupt cessation can be followed by acute adrenal insufficiency.
  • Under the same conditions, salicylic acid can be responsible for salicylic intoxication.

PRECAUTIONS FOR USE

  • In infants, it is preferable to avoid corticosteroids of very strong, strong or moderate activity. One should be particularly wary of spontaneous occlusion phenomena which may occur in folds or under layers.
  • This medication should be used with caution, especially in children, in all circumstances likely to favor a systemic passage.
  • In the event of renal insufficiency, the treatment of a skin affection of great extent requires special monitoring because of the possible effects caused by the transcutaneous absorption of salicylic acid.
  •  In the event of bacterial or mycotic infection of a corticosensitive dermatosis, precede the use of the corticosteroid with a specific treatment.
  •  If a local intolerance appears, the treatment must be interrupted and the cause must be sought.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • No teratogenicity studies have been performed with topical corticosteroids.
  • However, studies concerning the intake of oral corticosteroids have not revealed a higher risk of malformation than that observed in the general population.
  • Therefore, this medication can be prescribed during pregnancy if needed.

Breastfeeding

  • Do not apply to the breasts during breastfeeding, because of the risk of ingestion of the product by the newborn.

What happens if I overdose from KENALCOL ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What should I do if I miss a dose?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking KENALCOL ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Lack of information in the MA.
  • 25 ml yellow (brown) glass bottle with acetal resin low density polyethylene (LDPE) metering pump.

Composition-


Solution for skin application
Active ingredient

Triamcinolone

  • 0.178 g *

Salicylic acid

  • 1.78 g *

Benzalkonium chloride

  • 0.089 g ** per unit dose

Active ingredients: Triamcinolone , Salicylic acid , Benzalkonium chloride

Excipients: Purified water , Alcohol

No excipient with known effect is not present in the composition of this drug

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.

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