TRANSIPEG Powder for oral solution Uses, Dosage, Side Effects & Precautions
what is TRANSIPEG ?
This medication is indicated for the symptomatic treatment of constipation in adults.
PRESENTATION (S) AVAILABLE FOR TRANSIPEG 5.9 G
6 presentations are available for this medication:
- 10 sachet (s) of 6.975 g polyethylene aluminum foil
- 20 polyethylene aluminum foil sachet (s) of 6.975 g
- 30 polyethylene aluminum foil sachet (s) of 6.975 g
- 50 polyethylene aluminum foil sachet (s) of 6.975 g
- 60 polyethylene aluminum foil sachet (s) of 6.975 g
- 200 sachet (s) of 6.975 g polyethylene aluminum foil
|Active substance (s)||for a sachet: macrogol 3350 (5.9 g)|
|Pharmaceutical form||powder for oral solution|
|Route (s) of administration||oral|
|Social security reimbursement rate||30 %|
|Laboratory (s)||BAYER FAMILY HEALTH|
|Conditions of issue||restricted prescription drug|
what is TRANSIPEG medication used for and indication?
Symptomatic treatment of constipation in adults.
FOR ADULTS ONLY
- The dosage is 1 to 4 sachets per day in a single dose, preferably in the morning. The average dosage is 2 sachets per day.
- Each sachet must be dissolved in 50 ml of water, the equivalent of half a glass of water. The solution should be drunk shortly after reconstitution.
- The effect of Transipeg is manifested within 24 to 48 hours of administration.
Elderly subject or subject suffering from renal failure:
- No dosage adjustment is necessary.
- The treatment should be taken over a short period.
- Hypersensitivity to the active principle or to any of the excipients.
- Severe inflammatory colopathies (such as ulcerative colitis, Crohn’s disease) and toxic megacolon.
- Perforation / risk of perforation.
- Occlusive or subocclusive syndrome, symptomatic stenoses.
- Painful abdominal syndromes of undetermined cause.
- Phenylketonuria, due to the presence of aspartame.
- Due to the presence of sucrose , this medication is contraindicated in cases of fructose intolerance, glucose and galactose malabsorption syndrome or sucrase-isomaltase deficiency.
HOW TO TAKE TRANSIPEG?
- TRANSIPEG 5.9 g powder for oral solution in sachet should only be taken over a short period.
- The effect of TRANSIPEG 5.9 g, powder for oral solution in sachet is manifested within 24 to 48 hours after taking.
how does TRANSIPEG work?
- The electrolyte content of the reconstituted solution is such that the electrolytic exchanges between the intestine and the plasma can be considered as zero.
- Pharmacokinetic data confirm the absence of digestive absorption and biotransformation of macrogol 3350 after oral ingestion.
HOW TO STORE TRANSIPEG?
- Keep this medication out of the sight and reach of children.
- Do not use this medicine after the expiry date which is stated on the package. The expiration date refers to the last day of that month.
- No special storage conditions.
- Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.
TRANSIPEG Side Effects
Like all medicines, TRANSIPEG 5.9 g powder for oral solution in sachet can cause side effects, although not everybody gets them.
- Very rare cases of anaphylactic reactions (serious allergic reaction causing difficulty in breathing, swelling, etc.) and allergic reactions such as urticaria (appearance of red patches), skin rash, pruritus (itching) or edema (swelling), have been reported. If these reactions appear, stop treatment immediately and seek advice from your doctor.
- Abdominal pain and bloating have also been reported frequently, particularly in subjects with intestinal disorders.
- The onset of mild diarrhea, or watery stools is a common side effect, especially if the dose is too high.
These effects usually go away within 24 to 48 hours after stopping treatment. Treatment can then be resumed at a lower dose.
If you experience any of the side effects listed as serious, or if you experience any side effects not listed in this leaflet, please tell your doctor or pharmacist.
Keep out of the reach and sight of children.
All available data provided by trials and clinical experience have shown the absence of interactions between TRANSIPEG and other medicinal products.
Drive and use machines
No effect on the ability to drive and use machines has been observed.
Warnings and Precautions
- The drug treatment of constipation is only an adjunct to the hygieno-dietetic treatment:
- Enriching the supply of vegetable fiber and drink,
- Advice on physical activity and rehabilitation of the exemption.
- If people, using this medicine for the first time, do not get any improvement in their condition after 2 weeks, they should seek advice from their doctor.
- Due to the presence of aspartame, this drug is contraindicated in cases of phenylketonuria.
- This medicine contains sucrose. Patients with fructose intolerance, glucose-galactose malabsorption syndrome, or sucrase / isomaltase deficiency (rare inherited diseases) should not take this medicine.
- This medicinal product contains 145 mg of sodium per sachet, equivalent to 7.25% of the maximum daily food intake recommended by the WHO of sodium (2 g) per adult. The maximum daily intake of this product is equivalent to 29% of the WHO recommended maximum daily dietary intake of sodium (2 g) per adult. TRANSIPEG is considered to be a ‘high sodium’ medicine. To be taken into account in patients on a controlled sodium diet.
Precautions for use
- This medicine contains polyethylene glycol. Rare allergic-type manifestations and exceptional cases of anaphylactic shock have been reported only for high doses of polyethylene glycol, used in colonic exploration preparations.
- Two sachets of this medicine contain 1 mmol (40 mg) of potassium. Take it into account in the daily ration in case of renal insufficiency or of a controlled potassium diet.
PREGNANCY & BREAST-FEEDING & FERTILITY
- There are no clinical data available on pregnancies exposed to macrogol 3350. Animal studies have not produced any evidence of a teratogenic effect.
- Consequently, and taking into account the very low absorption of macrogol 3350, the use of TRANSIPEG 5.9 g can be considered if necessary.
- There are no data on the excretion of macrogol 3350 in milk. As macrogol 3350 is poorly absorbed, and when necessary, the prescription of TRANSIPEG 5.9 g may be considered during breast-feeding.
What happens if I overdose from TRANSIPEG?
Overdose results in diarrhea leading to temporary discontinuation of treatment or reduction of dosage. Heavy fluid loss during diarrhea may require correction of electrolyte disturbances.
What should I do if I miss a dose?
Do not take a double dose to make up for the single dose you forgot to take.
What is Forms and Composition ?
Packaging size: 200 sachets.
- TRANSIPEG 5.9 g Powder for oral solution sachets box of 20
- TRANSIPEG 5.9 g Powder for oral solution sachets box of 200
- TRANSIPEG 2.95 g Powder for oral solution sachets box of 30
- The active substance is macrogol 3350 (5.9 g per sachet).
- Other ingredients sodium chloride, anhydrous sodium sulfate (E514), potassium chloride (E508), sodium bicarbonate (E500), aspartame (E951), acesulfame potassium, lemon flavoring.
- The lemon flavor contains: maltodextrin, sucrose, lemon flavor, gum arabic (E414), lecithin (E322) and silicon dioxide (E551).
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- Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
- General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
- For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
- It treats possible side effects and drug interactions that require attention and its effect on continuous use.
- The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.