Instillagel 230 mg / 5.75 mg Uses, Dosage, Side Effects, Precautions & Warnings
INSTILLAGEL, urethral gel in pre-filled syringe, box of 10 pre-filled syringes of 11 ml >>> Generic drug of the Therapeutic class: Anesthesia, resuscitation, analgesics,
active ingredients: Lidocaine , Chlorhexidine
Table of Contents
what is Instillagel ?
This medicine is a local anesthetic.
what is Instillagel medication used for and indication?
This medication is recommended in all anesthesias before exploration of the urinary tract.
Presentation (s) available for Instillagel
2 presentations are available for this medication:
- 1 11 ml polypropylene pre-filled syringe (s)
- 10 polypropylene pre-filled syringe (s) of 11 ml
| FEATURE | DESCRIPTION |
| Pharmaceutical class | not communicated |
| Active substance (s) | for an 11 ml pre-filled syringe: lidocaine hydrochloride (230.00 mg), chlorhexidine digluconate solution |
| General medicine | no |
| Pharmaceutical form | gel |
| Route (s) of administration | urethral |
| Selling price | unregulated price |
| Social security reimbursement rate | 0% |
| Laboratory (s) | Instillagel manufacturer laboratory (ies) |
| Conditions of issue | available by simple prescription |
Instillagel Dosage
- The usual dosage is one syringe, not to exceed 2 in humans.
- IN ALL CASES, STRICTLY COMPLY WITH THE MEDICAL PRESCRIPTION.
Instillagel Contraindications
Never use INSTILLAGEL, urethral gel in a pre-filled syringe in the following cases:
- allergy to lidocaine and local anesthetics of the same chemical group,
- allergy to chlorhexidine,
- porphyria (congenital diseases of red blood cells),
- epilepsy not controlled by treatment.
IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.
How To Take Instillagel ?
Method and route of administration
- After disinfection of the urinary meatus with a mild cationic antiseptic, instill the contents of the syringe into the urethra. Then apply a soft forceps at the level of the balano-pepucial groove. Anesthesia is obtained after about 5 minutes.
- IN ALL CASES, STRICTLY COMPLY WITH YOUR DOCTOR’S ORDER.
Frequency of administration
- It is recommended to use this medication from the first maneuver, in order to avoid too much blood flow of lidocaine through a frayed mucous membrane.
Duration of treatment
- IN ALL CASES, STRICTLY COMPLY WITH THE MEDICAL PRESCRIPTION.
how does Instillagel work?
Pharmacotherapeutic group:
Pharmacotherapeutic group: LOCAL ANESTHESICS, ATC code: N01BB52 (N: central nervous system)
- Lidocaine is an amide-linked local anesthetic.
How To Store Instillagel ?
- Do not use this medicine after the expiry date which is stated on the outer packaging.
- This medication should be stored at a temperature below 25 ° C and protected from moisture.
- Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment
Instillagel Side Effects
Like all medicines, INSTILLAGEL, urethral gel in syringe can cause side effects, although not everybody gets them.
Linked to lidocaine
Toxic reactions (exceptional with the forms used locally) can appear under two conditions: either immediately by relative overdose, due to accidental intravenous passage, or later by true overdose, due to the use of too much large amount of anesthetic.
We could observe:
- in terms of the central nervous system:
- nervousness, restlessness, yawning, trembling, apprehension, involuntary eye movements, overwhelming urge to speak, headache, nausea, ringing in the ears. These warning signs require careful monitoring on the lookout for a possible aggravation: convulsions then depression of the central nervous system.
- on the respiratory level:
- rapid breathing then difficult.
- on the cardiovascular level:
- tachycardia, hypertension, likely to be followed by signs of depression, hypotension, bradycardia preceding cardiac arrest.
Linked to the presence of chlorhexidine
- Allergic reaction on the skin.
TELL YOUR DOCTOR OR YOUR PHARMACIST OF ANY UNINTENDED AND HARMFUL EFFECT THAT IS NOT MENTIONED IN THIS PACKAGE LEAFLET.
Keep out of the reach and sight of children.
Instillagel Interactions
Known interactions with lidocaine (antiarrhythmics, beta-blockers), in principle, do not concern topical use. However, take into account a risk of systemic passage of lidocaine in the event of an injured mucosa.
Chlorhexidine is a cationic anti-bacterial. It is incompatible with all anionic derivatives (soaps).
Effects on ability to Drive and use machines
This product can modify the reaction capacities for driving vehicles or using machines, in the event of too much blood flow.
Warnings and Precautions
Special warnings
- Do not inject intramuscularly or intravenously.
- This medicine contains methyl propyl parahydroxybenzoate and may cause allergic reactions.
- This medicine contains propylene glycol and may cause skin irritation.
Precautions for use
Use this medication WITH CAUTION in case of:
- of use in children, the amount administered will depend on the weight and age of the child.
- traumatized or inflammatory urethral mucosa.
IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.
PREGNANCY & BREAST-FEEDING & FERTILITY
Feeding with milk
Based on the available data, use in pregnant or breastfeeding women is possible.
Fertility
So far, there is no evidence that lidocaine interferes with fertility.
What happens if I overdose from Instillagel ?
Manifestations of neurological toxicity due to the presence of lidocaine are treated by injection of a short-acting barbiturate or a benzodiazepine, oxygenation, assisted ventilation.
In the event of accidental massive oral ingestion, perform gastric evacuation (presence of surfactants).
What should I do if I miss a dose?
- Not applicable.
- Not applicable.
- Not applicable.
- Not applicable.
- Not applicable.
What happens if you stop taking Instillagel ?
- Not applicable.
- Not applicable.
- Not applicable.
- Not applicable.
- Not applicable.
If you have any further questions about the use of this medicine, ask your doctor, pharmacist or nurse for more information.
What is Forms and Composition ?
SHAPES and PRESENTATIONS
- Urethral gel (sterile): Pre-filled syringes of 11 ml, single use, box of 10, in single thermoformed trays. Pre-filled syringes of 11 ml, single use, box of 10, in single thermoformed trays.
COMPOSITION
| p syringe | |
| Lidocaine hydrochloride | 230 mg |
| Chlorhexidine gluconate | 5.75 mg |
- Excipients: propylene glycol, hydroxyethylcellulose, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), sodium hydroxide, purified water.
- Excipients with known effect: methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), propylene glycol (5.75 g / 11 ml; this is equivalent to 522.5 mg / ml).
NOT’s
Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:
general information:
- Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles
Additional information:
- General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.
Special warnings:
- For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.
Side effects:
- It treats possible side effects and drug interactions that require attention and its effect on continuous use.
- The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.