Posine, eye drops Uses, Dosage, Side Effects, Precautions & Warnings

POSINE, eye drops, solution, 10 ml dropper bottle
79 / 100

Generic drug of the Therapeutic class: Ophthalmology
Active ingredients: Chlorhexidine , Synephrine

Medicinal product withdrawn from the market on 07/03/2006

what is Posine ?

This medication is usually prescribed for:

  • Non-infectious conjunctival irritation

what is Posine medication used for and indication?

Adjunctive treatment of non-infectious conjunctival irritations.

Posine Dosage

  • Local route.
  • One drop of eye drops 2 to 4 times a day.
  • Instill 1 drop of eye drops in the lower conjunctival cul-de-sac of the diseased eye (s) by looking upwards and pulling the lower eyelid slightly downwards.
  • Do not touch the eye or the eyelids with the tip of the bottle.
    Recap the bottle after use.

Posine Contraindications


This medication is contraindicated in the event of:

  •  hypersensitivity to one of the constituents of the eye drops,
  • risk of glaucoma by closing the angle.


This medication is generally not recommended in the following situations:

during the first trimester of pregnancy and in case of breastfeeding:

  • pregnancy: there are no reliable data on teratogenesis in animals.
  • There is currently no relevant, or sufficient number, to assess a possible malformative effect of synephrine when administered during pregnancy.
  • Consequently, the use of drugs containing synephrine is not recommended during the first trimester.
  • Breast-feeding: due to the lack of data on the passage of this drug in breast milk, the use of this one should be avoided during breast-

Posine Side Effects

  • feeding.
  • in combination with bromocriptine; guanethidine and related; non-selective MAOIs (iproniazid, nialamide) (see interactions).

how does Posine work?

  • Risk of acute glaucoma by closing the angle.
  • Possibility of transient irritation.
  • Possibility of allergic reactions: blepharitis, conjunctivitis.
  • Repeated instillations can cause an annoying mydriasis, superficial punctate keratitis; exceptionally, by systemic effect of synephrine, an increase in blood pressure, tremors, pallor, headaches, cardiac arrhythmias.


Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.

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