gaviscon drug Uses, Dosage, Side Effects, Precautions & Warnings

what gaviscon used for
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gaviscon drug >> Generic drug of the Therapeutic class: Gastro-EnteroHepatology
Active ingredients: Alginic acid (E400) , Sodium alginate (E401) , Aluminum hydroxide , Sodium bicarbonate (E500)

what is gaviscon used for and indication?

Symptomatic treatment of gastroesophageal reflux.

how to take gaviscon?

  1. 2 teaspoons 3 times a day after the 3 main meals and possibly evening at bedtime.
  2. This dosage may be doubled in case of severe reflux or esophageal inflammation.

Contraindications

  • Sodium alginate hypersensitivity
  • Sodium bicarbonate hypersensitivity
  • Parabens hypersensitivity

Hypersensitivity to the active substances or to any of the excipients listed in the Composition section.

how does gaviscon work?

OTHER MEDICINES FOR PEPTIC ULCER AND GASTRO-ESOPHAGEAL REFLUX (GERD).

ATC Code: A02BX.

The physico-chemical characteristics of the GAVISCON gel, formed in contact with acidic gastric fluid, give it the following 3 properties:

  1. Its lightness allows it to float above the gastric contents at the level of the gastro-oesophageal junction,
  2. Its viscosity and coherence form a physical barrier that opposes the reflux (decrease in the number of reflux). In case of severe reflux, the gel regurgitates first in the esophagus and interposes between the esophageal wall and irritating gastric fluid,
  3.  Its alkaline pH replaces the acidic pH of the reflux liquid. Gastric pH shows that administration of GAVISCON increases the pH of 2 units in the cardia but does not change the pH in the rest of the stomach.

Its pharmacological efficacy is confirmed by studies of esophageal pH-metrics that show that GAVISCON significantly reduces the percentage of total time spent at acid pH in the esophagus (pH <4), as well as the number and the average duration of episodes of reflux.

In particular, the efficacy of GAVISCON on reflux symptoms has been established in patients with previously scarred grade I or II esophagitis.

does gaviscon have side effects?

Related to calcium carbonate:

  • · Possible constipation, which is exceptional thanks to the presence of alginate.
  • · In prolonged use, possible hypercalcemia with risk of nephrolithiasis and renal failure.

Allergic manifestations such as urticaria, bronchospasm, anaphylactic or anaphylactoid reactions have been reported.

gaviscon medication interactions?

Antacids interact with some other drugs taken orally.

Associations subject to precautions for use

There is a decrease in digestive absorption of drugs administered simultaneously.

As a precaution, antacids should be taken away from other drugs.

Space this medication for more than 2 hours, if possible, with:

  1. Antibacterials-antituberculous (ethambutol, isoniazid) ( oral )
  2. Antibacterial cyclines ( oral )
  3. Antibacterials-lincosanides ( oral )
  4. Antihistamines H 2 ( oral )
  5. Atenolol, metoprolol, propranolol ( oral )
  6.  Chloroquine ( oral )
  7. Diflunisal ( oral )
  8.  Digoxin ( oral )
  9.  Diphosphonates ( oral )
  10. Sodium fluoride
  11. Glucocorticoids ( oral ) (described for prednisolone and dexamethasone)
  12. Indomethacin (oral)
  13. Kayexalate ( oral )
  14. Ketoconazole ( oral )
  15. Lansoprazole
  16. Phenothiazinic neuroleptics ( oral route )
  17. Penicillamine ( oral )
  18. Iron salts ( oral )
  19. Sparfloxacin ( oral )

Space this medication for more than 4 hours, if possible, with:

  1.  Antibacterials-fluoroquinolones ( oral )

Associations to consider

  1. Salicylates (oral) :
Drug with same Active ingredient

Increased renal excretion of salicylates by alkalinization of urine.

GAVISCON Warnings and Precautions

This medicine contains calcium. Each sachet contains 160 mg of calcium carbonate. Precautions should be taken in patients with hypercalcemia, nephrocalcinosis and kidney stones.

Drive and use machines

GAVISCON and PREGNANCY / BREAST FEEDING / FERTILITY

gaviscon when pregnant

  1. Clinical studies conducted in more than 500 pregnant women, as well as a large amount of data from the post-marketing experience, revealed no malformative or toxic effects of the active substances for the fetus or newborn. .
  2. Gaviscon can be used during pregnancy, if necessary.

Breastfeeding

  1. No effect of the active substances was found in neonates / infants breastfed by a treated woman. Gaviscon can be used during breastfeeding.

Fertility

  1. Clinical data do not suggest that Gaviscon has an effect on human fertility at therapeutic doses.

What happens if I overdose from?

In case of overdose, the treatment is symptomatic. The patient may have abdominal distension.

What is  Forms and Composition?

COMPOSITION
Oral suspension in sachet: p bag
Sodium alginate 500 mg
Sodium bicarbonate 267 mg
  • Excipients: calcium carbonate, carbomer (974P), sodium saccharin, natural mint flavor, sodium hydroxide, purified water. Preservatives: methyl parahydroxybenzoate (E 218) and propyl parahydroxybenzoate (E 216).
  • Excipients with known effect: Each sachet contains 145 mg (or 6.3 mmol) of sodium, 40.00 mg of methyl parahydroxybenzoate (E218) and 6.00 mg of propyl parahydroxybenzoate (E216).
Oral suspension in a bottle: p 10 ml
Sodium alginate 500 mg
Sodium bicarbonate 267 mg
  • Excipients: calcium carbonate, carbomer (974 P), sodium saccharin, fennel flavor (fennel anethole, benzyl alcohol), sodium hydroxide, erythrosine (E127), purified water. Preservatives: methyl parahydroxybenzoate (E 218) and propyl parahydroxybenzoate (E 216).
  • Excipients with known effect: 100 ml of suspension contain 1.45 g (63 mmol) of sodium, 0.400 g of methyl parahydroxybenzoate (E218) and 0.060 g of propyl parahydroxybenzoate (E216).
  • 1 ml contains 50 mg of sodium alginate and 26.7 mg of sodium bicarbonate.

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.

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