The text below is about the active substance Chlorobutanol .
what is chlorobutanol?
Chlorobutanol is a detergent preservative that has been included in a wide spectrum of cosmetic and pharmaceutical products because of its antibacterial and antifungal properties.
However, its use as an ophthalmic preservative has become limited due to its instability when stored at room temperature for an extended period of time.
chlorobutanol mechanism of action
Chlorobutanol acts as a local anesthetic.
what is chlorobutanol used for?
In combination with propionic acid and hexetidine, chlorobutanol is used in the management of oral disorders.
- Infections of the oral cavity,
- postoperative care in stomatology.
In combination with levomenthol , chlorobutanol is used in the management of:
- endonasal interventions,
- post-traumatic crusted rhinitis.
what nasal spray contains chlorobutanol?
chlorobutanol side effects
chlorobutanol does not affect the stability of the lipid component of the tear film17 and in vitro studies have shown that it is less toxic to rabbit corneal epithelial cells, in comparison to BAK.
In human corneal epithelial cells, the cytotoxic effects of chlorobutanol occurred less rapidly and were less severe than cells exposed to BAK.