Browsing Tag

Chlorobutanol

The text below is about the active substance Chlorobutanol .

what is chlorobutanol?

Chlorobutanol is a detergent preservative that has been included in a wide spectrum of cosmetic and pharmaceutical products because of its antibacterial and antifungal properties.

However, its use as an ophthalmic preservative has become limited due to its instability when stored at room temperature for an extended period of time.

chlorobutanol mechanism of action

Chlorobutanol acts as a local anesthetic.

what is chlorobutanol used for?

In combination with propionic acid and hexetidine, chlorobutanol is used in the management of oral disorders.

In combination with chlorhexidine , eugenol and cetylpyridium, or choline salicylate and hexetidine, chlorobutanol is used in the management of:

Infections of the oral cavity,
postoperative care in stomatology.

In combination with levomenthol , chlorobutanol is used in the management of:

endonasal interventions,
post-traumatic crusted rhinitis.

Medicines containing the active substance alone (0)

Medicines containing the active substance in combination (12)

what nasal spray contains chlorobutanol?

Angispray

chlorobutanol side effects

chlorobutanol does not affect the stability of the lipid component of the tear film¹⁷ and in vitro studies have shown that it is less toxic to rabbit corneal epithelial cells, in comparison to BAK.

In human corneal epithelial cells, the cytotoxic effects of chlorobutanol occurred less rapidly and were less severe than cells exposed to BAK.