Daivonex ointment Uses, Dosage, Side Effects, Precautions & Warnings

DAIVONEX 50 micrograms / gram, ointment
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DAIVONEX 50 micrograms / gram, ointment >>> Generic drug of the Therapeutic class: Dermatology
Active ingredients: Calcipotriol

what is Daivonex ointment used for and indication?

This medication is a cream for topical application containing a derivative of vitamin D.

It is recommended in the treatment of psoriasis.


3 presentations are available for this drug:

  • 1 painted aluminum tube (s) of 30 g
  • 1 tube (s) painted aluminum of 100 g
  • 1 120 g painted aluminum tube (s)
Pharmaceutical class psoriasis treatment
Active substance (s) calcipotriol monohydrate
General medicine no
Pharmaceutical form cream
Route (s) of administration cutaneous
Social security reimbursement rate 65%
Laboratory (s) LEO
Conditions of issue available by simple prescription

Daivonex Dosage

  • An application morning and evening to the lesions. In maintenance treatment and depending on the results, the frequency of applications may be reduced to once a day.
  • The maximum dose to apply is 100 g of cream per week.
  • In the event of concomitant use of DAIVONEX ointment, this maximum dose of 100 g per week should take into account the amount of ointment used.
  • Calcipotriol cream can be usefully combined with local corticosteroids, and in more widespread forms of psoriasis, with phototherapy, ciclosporin or acitretin, respecting the maximum dose of 100 g of cream per week and, in applying to a body surface area of ​​less than 40%.
  • If combined with topical corticosteroids, one of the treatments will be applied in the morning, the other in the evening.
  • In children, clinical efficacy and safety data are very limited. In clinical studies DAIVONEX was only used in 79 children aged 6 to 12 years and 19 children over 12 years of age for 6 to 8 weeks. The average dose applied per week (approximately 15 grams) was often lower than the maximum dose allowed in clinical studies (50 grams for the age of 6 to 12 years and 75 grams for the age of 12 to 16 years). Under these conditions, the treatment was well tolerated.
  • The possible impact on bone growth from prolonged treatment with topical calcipotriol is not known.

Daivonex Contraindications

Never use DAIVONEX 50 micrograms / gram, cream in case of:


  • History of allergy to calcipotriol or to one of the excipients.
  • Hypercalcemia whatever the origin.
  • The cream should not be applied to the face.


  • In the absence of clinical data, the use of calcipotriol in other forms of psoriasis is not recommended (pustular, gouty, erythrodermic psoriasis).
  • Breast-feeding: it is not known whether calcipotriol passes into breast milk.

How To Take Daivonex ?

Administration mode

  • Dermal.

Frequency of administration

  • For best results, apply the cream twice a day, once in the morning and once in the evening.
  • Depending on the results, your doctor may instruct you to apply the cream only once a day.

how does Daivonex work?


Calcipotriol is a structural analogue of vitamin D. Calcipotriol allows differentiation and inhibits the proliferation of keratinocytes in vitro, thus correcting the abnormality of these cells observed during psoriasis.

How To Store Daivonex ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month. The tube should be discarded 6 months after first use.
  • Store the tube at a temperature not exceeding 25 ° C.
  • Do not freeze.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

Daivonex Side Effects

Like all medicines, DAIVONEX 50 micrograms / gram, cream can cause side effects, although not everybody gets them:

  • Skin irritation may occur in the lesions treated, usually not requiring discontinuation of treatment; If the irritation persists, report it to your doctor.
  • Possibility of skin irritation on the face: this should not occur if the hands are washed properly after application.
  • If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
  • Keep out of the reach and sight of children.

Daivonex Ointment Interactions

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

daivonex ointment Warnings and Precautions

Special warnings

  • Do not apply under an occlusive dressing, or in the folds without first consulting your doctor.

Precautions for use

  • Do not apply on the face. Applying DAIVONEX 50 micrograms / gram, cream to the face may cause local irritation. Wash hands after each use to avoid accidental transfer to the face or mouth.
  • Do not exceed the maximum dose prescribed by your doctor.
  • Avoid excessive exposure to natural or artificial light and any other form of treatment with light rays.
  • If in doubt, do not hesitate to seek the advice of your doctor or pharmacist.



  • There are no data from the use of calcipotriol in pregnant women.
  • Oral animal studies have shown reproductive toxicity.
  • Daivonex should not be used during pregnancy unless clearly necessary.

Feeding with milk

  • There are no data on the excretion of calcipotriol in human milk.
  • Caution should be exercised when prescribing Daivonex to breast-feeding women. The patient should be instructed not to use Daivonex on the breasts while breastfeeding.


  • Studies in rats have shown no impairment of fertility in males and females after oral administration of calcipotriol.

What happens if I overdose from Daivonex ?

Immediately consult your doctor or pharmacist.

What should I do if I miss a dose?

Do NOT apply a double dose to make up for the dose you forgot to apply.

What happens if you stop taking Daivonex ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?


  • Ointment.
  • 120 g painted aluminum tube.

Other shapes

  • DAIVONEX 50 micrograms / gram, cream, 30 g tube
  • DAIVONEX 50 micrograms per ml, solution for scalp, 60 ml vial
  • DAIVONEX 50 micrograms / gram, ointment, 30 g tube
  • DAIVONEX 50 micrograms / gram, cream, 120 g tube
  • DAIVONEX 50 micrograms per ml, solution for scalp, 120 ml vial


p 100 g
Calcipotriol (as calcipotriol monohydrate) 0.005 g
  • Excipients: sodium edetate, sodium hydrogenphosphate dihydrate, liquid paraffin (containing all-rac-alpha-tocopherol), petrolatum (containing all-rac-alpha-tocopherol), 85 percent glycerol, ketostearyl ether macrogol, alcohol cetostearyl, diazolidinyl urea, 2,4-dichlorobenzyl alcohol, sodium hydroxide (for pH adjustment), purified water.
  • Excipients with known effect: Each g of cream contains 72 mg of cetostearyl alcohol, 1 mg of dichloro -2.4 benzyl alcohol, and 3 mg of diazolidinyl urea.


Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.

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