Browsing Tag

calcium phosphate

The text below is about the active substance Calcium phosphate .

Important to know about calcium phosphate with vitamin D.

  • Calcium (lime) is necessary for the bones and teeth. Vitamin D (colecalciferol) ensures that you can absorb calcium and phosphate from food.
  • In case of a shortage of calcium and vitamin D, bone loss (osteoporosis) or to prevent it in people who have a high risk of this. Such as some postmenopausal women and people on long-term adrenal cortex hormones.
  • After a few months you have less chance of fractures. You will usually take this medicine for several years.
  • Dissolve the powder in a glass of water. Then drink it right away.
  • Choose a fixed intake time, preferably with an evening meal. Be careful not to use grain products, bran, rhubarb or spinach along with calcium phosphate. This means that calcium is less well absorbed.
  • You may feel sick or have constipation, diarrhea or stomach pain. Consult your doctor if this affects you.
  • Have you ever had kidney stones? Then talk to your doctor. You are more likely to do this. You reduce the risk of kidney stones if you drink at least 2 liters of fluids throughout the day.
  • There are interactions with other means. Ask your pharmacist if you can safely use calcium phosphate with vitamin D with your other medications.

What does calcium phosphate do with vitamin D and what do I use it for?

Calcium (lime) is important for the structure and strength of bones and teeth.

Vitamin D (colecalciferol) ensures the absorption of calcium and phosphate from the food. Calcium and phosphate are necessary for the proper construction of bones and teeth.

The combination of calcium phosphate and colecalciferol is used for a lack of calcium and vitamin D and for osteoporosis .

Vitamin and mineral deficiency

For sufficient vitamins and minerals, you need an average of two hundred grams of vegetables and two pieces of fruit a day. Whole grain products, meat and fish also contain important vitamins and minerals. Most people get enough vitamins and minerals through their food. Calcium includes milk (products), vegetables, nuts and legumes. Vitamin D is found in fatty fish and animal fat. It has also been added to margarine, low-fat margarine and baking and roasting products.


Calcium (lime) is important for the structure and strength of bones and teeth. Calcium is also needed for blood clotting, muscle contraction, proper functioning of the nervous system and for the production of various types of enzymes and hormones. Colecalciferol is a form of vitamin D. Vitamin D ensures the absorption of calcium and phosphate from the food. Too little calcium or vitamin D in the food is usually never the only cause of a deficiency. Usually there are:

  • A reduced parathyroid function. There is a balance between the amount of vitamin D, calcium (calcium), phosphate and parathyroid hormone. People with reduced parathyroid function produce insufficient or no parathyroid hormone.
  • Kidney Diseases. In people with renal dysfunction the balance between calcium (calcium), phosphate, vitamin D and parathyroid hormones in the blood is disturbed.
  • A condition that makes it harder for calcium and vitamin D to be absorbed from food.


Usually you will hardly notice a shortage of calcium or vitamin D. With a severe deficiency in the body you may experience muscle cramps, muscle weakness, muscle pain, bone pain and fractures due to weakened bones.

How it works

This remedy supplements the shortage of calcium and vitamin D in the body. The symptoms of the deficiency disappear in a few weeks to months.

Bone decalcification


In osteoporosis, the bones become more fragile. They are more likely to fracture and the vertebrae of the spine collapse. You will not notice that you have osteoporosis yourself. The doctor can check the strength of the bones with a bone density test.


Bone decalcification occurs because the bones absorb too little calcium (calcium). There should be a constant balance between the production and breakdown of bones. With bone loss (osteoporosis), the breakdown is stronger than the production.

When can bone loss occur?

Bone decalcification can occur under various circumstances. The most important are the following.

  • Higher age. From about the age of 45, the production of bones is less than the breakdown. This is the case for both men and women, but men generally have stronger bones than women, so they are less likely to suffer from osteoporosis.
  • Menopause in women. The body then produces less estrogens. Estrogens are female sex hormones that also balance the production and breakdown of bone tissue. The less estrogens, the weaker the bones.
  • Removal of the ovaries in women, as the ovaries produce estrogens that help build bone.
  • Long-term use of many adrenal hormones (corticosteroids), such as prednisone, or certain medications used in breast cancer and prostate cancer. These have bone loss as a side effect.
  • Not enough exercise . Movement stimulates bone growth.
  • Too little vitamin D . Vitamin D ensures that the bones absorb calcium. It is made in the skin under the influence of sunlight. If you don’t spend much time outdoors, you run the risk of too little vitamin D.


  • This medicine supplements a shortage of calcium and vitamin D. Vitamin D ensures that the bones absorb more calcium. You will not notice the effect of calcium and vitamin D in osteoporosis. You are only less likely to break bones.

What are possible side effects?

In addition to the desired effect, this can cause drug side effects.

The main side effects are the following.

Rare (affects 1 to 10 in 100 people)

  • Gastrointestinal complaints , such as nausea, constipation, diarrhea and stomach pain. Consult your doctor if this affects you.

Very rare (affects less than 1 in 100 people)

  • Kidney stones . If you’ve ever had kidney stones, see your doctor. You have a better chance of this. You reduce this chance if you drink enough water or tea, at least 2 liters per day spread throughout the day.
  • Hypersensitivity . You may notice this by a rash, hives and itching. In rare cases, breathlessness or fainting develops. Then contact a doctor immediately. In either case, you should not use this medicine in the future. Therefore, inform the pharmacist that you are hypersensitive to this medicine. The pharmacy team can then ensure that you do not receive this medicine again.

Very rare, and only with long-term use (months) of higher doses

  • Too much calcium in the blood , especially if you have reduced kidney or thyroid function. Do you have a sudden lack of appetite, muscle weakness, vomiting, constipation, severe thirst and need to urinate a lot? Then notify your doctor. These symptoms may indicate too much calcium. In dialysis patients, the blood will be checked regularly for too much calcium.
  • Too much phosphate in the blood. Dialysis patients should not use this drug, because this drug can give too much phosphate in their blood. This can cause complaints such as red eyes, itching, bone pain and cardiovascular disease.

Consult your doctor if you experience too much of any of the above side effects or if you experience any other side effects that worry you.

Explanation of frequencies

  • Regular : affects more than 30 in 100 people
  • Uncommon : affects 10 to 30 in 100 people
  • Rare : affects 1 to 10 in 100 people
  • Very rare : affects less than 1 in 100 people

How do I take this medicine?

Always check the pharmacy label for the correct dosage.


Dissolve the powder in a glass of water. Then drink it right away.


It is best to choose a fixed time, so that you will forget a dose less quickly. Preferably take this medicine during the evening meal, without consuming cereals, bran, rhubarb or spinach, as this will reduce the absorption of calcium in this medicine.

How long?

  • Shortage of calcium and vitamin D: often a shortage is eliminated within a few weeks to months.
  • Bone decalcification: you will probably need to take this medicine for a long time. Sometimes the doctor will take a bone density measurement.

What if I miss a dose?

It is important to take this medicine consistently. Therefore, choose fixed times. However, forgetting once in a while is not a problem. If you miss a dose, take the medicine anyway.

Can I drive a car, drink alcohol, and eat or drink anything with this medicine?

driving and drinking alcohol?

There are no restrictions for this with this medication.

eat everything?

Do not eat spinach, rhubarb, bran, and grain products at the same time you are taking this medication. These foods reduce calcium absorption. You can of course take these foods at a different time of the day.

Can I use calcium phosphate with vitamin D with other medications?

This drug interacts with other drugs. The text below only lists the active ingredients of these drugs, not the brand names. You can check whether your medicine contains one of these active substances in your package leaflet under the heading ‘composition’.

The medicines with which the main interactions occur are the following.

  • Other medicines for osteoporosis : alendronic acid, clodronic acid, etidronic acid, ibandronic acid and risedronic acid. Take these medications with calcium at least two hours before the medication.
  • Tetracycline-type antibiotics such as doxycycline, minocycline, tetracycline and demeclocycline. Take the antibiotics at least 2 hours before or 4 hours after the medication with calcium.
  • The antibiotics ciprofloxacin and norfloxacin. Take these antibiotics at least 2 hours before or 4 hours after the medication with calcium.
  • The thyroid hormones levothyroxine and liothyronine . Discuss this with your doctor. A different medication may be more suitable for you. You can also take these medications at least 2 hours before the medication with calcium or 4 hours after the medication with calcium.
  • The drug for bleeding disorders eltrombopag . Take eltrombopag at least 2 hours before or 4 hours after the medication with calcium.
  • Some HIV medications . Ask your pharmacist which medicines this concerns.

Not sure if any of the above interactions are of interest to you? Please contact your pharmacist or doctor.

Can I use this medicine if I am pregnant, planning to become or breastfeeding?


  • Do not use this medication if you are pregnant. This medicine contains too much vitamin D. You can safely use vitamin D in a dose of up to 10 micrograms (= 400IE) during pregnancy.
  • This combination contains twice as much vitamin D. This can be harmful to the baby. If you are taking this drug and you are thinking about getting pregnant, talk to your doctor. You can then switch to a different medication that contains less vitamin D.


  • If you want to breast-feed, talk to your doctor. This drug passes into breast milk in a small amount.
  • Are you on prescription or over-the-counter medications? Would you like to help increase knowledge about medication use during pregnancy and breastfeeding? Then report your experience to pREGnant .

Can I just stop taking this medicine?

You can stop taking this medicine at any time at once.

Under what names is calcium phosphate with vitamin D available?

The active substance calcium phosphate with vitamin D is contained in the following products:
  • Calisvit.

Do I need a prescription?

  • Colecalciferol has been on the market since 1930. 
  • Calcium Phosphate is on the market in 2010. 
  • The combination is available on prescription in sachets of powder under the brand name Calisvit.

what medicine contains calcium carbonate?