Dermatology Medicines – Drug Online https://edrug-online.com Medication Information Guide Mon, 23 Nov 2020 12:20:06 +0000 en-US hourly 1 https://wordpress.org/?v=5.6 cicatryl ointment Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1637/cicatryl-ointment.html https://edrug-online.com/1637/cicatryl-ointment.html#respond Mon, 23 Nov 2020 12:20:06 +0000 https://edrug-online.com/?p=1637 cicatryl ointmentGeneric drug of the Therapeutic class: Dermatology Active ingredients: Allantoin , Guaiazulene , Parachlorometacresol , Alpha-tocopherol (E307) what is cicatryl ointment medication used for and indication? CICATRYL ointment is used for the local treatment of minor wounds and superficial burns. PRESENTATION (S) AVAILABLE FOR CICATRYL 15 presentations are available for this drug: 1 polyethylene bag (s) painted aluminum foil of 2 g 3 sachet (s) […]]]> cicatryl ointment

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Allantoin , Guaiazulene , Parachlorometacresol Alpha-tocopherol (E307)

what is cicatryl ointment medication used for and indication?

CICATRYL ointment is used for the local treatment of minor wounds and superficial burns.

PRESENTATION (S) AVAILABLE FOR CICATRYL

15 presentations are available for this drug:

  • 1 polyethylene bag (s) painted aluminum foil of 2 g
  • 3 sachet (s) -dose (s) 4 g painted polyethylene aluminum foil – 14 sachet (s) -dose (s) 2 g painted polyethylene aluminum foil
  • 6 sachet (s) -dose (s) 2 g painted polyethylene aluminum foil – 6 sachet (s) -dose (s) 2 g painted polyethylene aluminum foil
  • 8 sachet (s) -dose (s) 2 g painted polyethylene aluminum foil – 8 sachet (s) -dose (s) 1 g painted polyethylene aluminum foil
  • 10 sachet (s) -dose (s) 2 g painted polyethylene aluminum foil – 2 sachet (s) -dose (s) 4 g painted polyethylene aluminum foil
  • 12 polyethylene sachet (s) – 2 g painted aluminum foil
  • 14 polyethylene sachet (s) – 2 g painted aluminum foil
  • 14 sachet (s) of 1 g painted polyethylene aluminum foil
  • 16 sachet (s) of 1 g painted aluminum polyethylene paper
  • 18 polyethylene sachet (s) – 2 g painted aluminum foil
  • 18 sachet (s) 1 g polyethylene aluminum coated paper
  • 20 sachet (s) of 1 g painted polyethylene aluminum foil
  • 24 polyethylene sachet (s) – 2 g painted aluminum foil
  • 28 polyethylene sachet (s) – 2 g painted aluminum foil
  • 140 polyethylene bag (s) painted aluminum foil of 2 g
FEATURE DESCRIPTION
Pharmaceutical class not communicated
Active substance (s) per 100 g: chlorocresol (0.120 g), alpha-tocopherol (acetate) (0.010 g), allantoin (1 g), guaiazulene (0.007 g)
General medicine no
Pharmaceutical form ointment
Route (s) of administration cutaneous
Selling price unregulated price
Social security reimbursement rate 0%
Laboratory (s) Laboratory (s) manufacturer Cicatryl
Conditions of issue available without prescription

cicatryl Dosage

Dosage

Wash hands thoroughly.

Apply a layer of Cicatryl on the affected skin area and massage it in with your fingertips.

As a general rule 1 or 2 applications per day to the affected skin region depending on the nature and extent of the injury or burn.

  • If the periphery of the wound is irritated, extend the application of CICATRYL widely beyond the wound to be treated.
  • If the wound or burn is too painful, cover it with gauze previously coated with CICATRYL.

cicatryl Contraindications

Never use CICATRYL ointment in sachet-dose:

  • If you are allergic (hypersensitive) to the active substances or to any of the other ingredients of CICATRYL, ointment in sachet-dose.

How to use cicatryl cream?

Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if in doubt.

Route of administration

  • Dermal.

After washing your hands, apply a layer of Cicatryl on the affected skin area and massage it in with your fingertips.

1 to 2 applications per day

The duration of treatment should not exceed 7 days. Beyond that, medical advice is required.

how does cicatryl work?

Pharmacotherapeutic group: DERMATOLOGICAL MEDICINES – EMOLLIENTS AND PROTECTORS: EMOLLIENTS AND PROTECTORS (OTHER EMOLLIENTS AND PROTECTORS) – ATC code: D02AX

This medicine contains a combination of the following active substances:

  • Allantoin aims to promote healing.
  • Alpha-tocopherol acetate ( vitamin E), is recognized for its anti-oxidant and anti-inflammatory properties.
  • Para-chlorometacresol is used as an antiseptic.
  • Guaiazulene is used for its anti-inflammatory properties.

How To Store cicatryl ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the outer packaging after EXP. The expiration date refers to the last day of that month.
  • Store at a temperature not exceeding 25 ° C.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

cicatryl Side Effects

Like all medicines, CICATRYL ointment in a sachet-dose can cause side effects, although not everybody gets them.

The following side effects may occur:

  • contact eczema,
  • an allergic reaction: (itching, redness of the skin and / or sudden swelling of the face and neck). If these reactions occur, you should stop treatment and seek medical advice promptly.

If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.

Keep out of the reach and sight of children.

cicatryl Interactions

Use of other drugs

  • If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

Special warnings

  • This medicine contains methyl parahydroxybenzoate (E 218) and propyl parahydroxybenzoate (E 216) and may cause allergic reactions.
  • These allergic reactions are.

Precautions for use

  • As is customary for any wound, prior cleaning is advised.
  • IN CASE OF DOUBT, DO NOT HESITATE TO ASK YOUR DOCTOR OR YOUR PHARMACIST FOR ADVICE.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • There are no or few data from the use of allantoin, chlorocresol, tocopherol acetate and / or guaiazulene in pregnant women.
  • Animal studies are insufficient with regard to reproductive toxicity. CICATRYL, ointment in sachet-dose is not recommended during pregnancy or in women of childbearing potential who are not using a contraceptive method.

Feeding with milk

  • There is no data available in animals and humans concerning the passage of the various active ingredients into breast milk. A decision should be made on whether to discontinue breast-feeding or treatment taking into account the benefit of breast-feeding for the child and the benefit of the treatment for the mother.
  • Do not apply to the breasts during breastfeeding.

Fertility

  • There are no human or animal data available to exclude a potential effect of allantoin, chlorocresol, tocopherol acetate and guaiazulene on male and female fertility.

What happens if I overdose from cicatryl ?

  • Not applicable.
  • Not applicable.
  • Not applicable.

What should I do if I miss a dose?

  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking cicatryl ?

  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Ointment.
  • Homogeneous and smooth ointment, blue in color.
  • 2 g in sachet (painted polyethylene-aluminum paper). Box of 14 sachets.

Other shapes

  • CICATRYL, ointment in sachet-dose, box of 28 sachets-doses of 2 g

Composition

Active ingredient Ointment
Allantoin 1 g *
Guaiazulene 0.007 g *
Parachlorometacresol 0.12 g *
Alpha-tocopherol acetate 0.01 g *

* per unit dose

  • Excipients with known effects Methyl parahydroxybenzoate, Propyl parahydroxybenzoate , Sorbitol (70 percent solution), Blend of: Cetostearyl alcohol (90 percent), Blend of: Cetostearyl alcohol (70 percent)
  • Other excipients:Light liquid paraffin, Vaseline, Glycerol monostearate, Macrogol glycol 400, Purified water, Sodium cetyl stearyl sulfate (10 percent), Sodium cetyl stearyl sulfate (10 percent), Ethoxylated fatty acid of organic origin (20 percent)

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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KENALCOL Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1679/kenalcol.html https://edrug-online.com/1679/kenalcol.html#respond Mon, 23 Nov 2020 12:20:00 +0000 https://edrug-online.com/?p=1679 KENALCOL, solution for skin applicationGeneric drug of the Therapeutic class: Dermatology Active ingredients: Triamcinolone , Salicylic acid , Benzalkonium chloride Medicinal product withdrawn from the market on 04/01/2008 what is KENALCOL medication used for and indication? Corticosteroid-sensitive dermatoses with a keratotic or squamous component: lichenification,  psoriasis (excluding large-plaque psoriasis), neurrodermatitis,  lichen planus, palmoplantar keratoderma. KENALCOL Dosage Treatment should be limited to 2 applications per day […]]]> KENALCOL, solution for skin application

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Triamcinolone , Salicylic acid , Benzalkonium chloride

Medicinal product withdrawn from the market on 04/01/2008

what is KENALCOL medication used for and indication?

Corticosteroid-sensitive dermatoses with a keratotic or squamous component:

  • lichenification,
  •  psoriasis (excluding large-plaque psoriasis),
  • neurrodermatitis,
  •  lichen planus,
  • palmoplantar keratoderma.

KENALCOL Dosage

  • Treatment should be limited to 2 applications per day for 2 weeks then 1 time per day.
  • The duration of treatment will not exceed 4 weeks.
  • On average, 1 to 2 ml per day, or 10 to 20 sprays.
  • Do not exceed 3 ml per day, or 30 sprays.
  • An increase in the number of daily applications may worsen the side effects without improving the therapeutic effects.
  • The treatment of large surfaces requires monitoring of the number of vials used.

KENALCOL Contraindications

  • Hypersensitivity to any of the products contained in the preparation, in particular to salicylates or to a related substance.
  •  Primary bacterial, viral, fungal or parasitic infections.
  • Ulcerated lesions.
  • Acne.
  • Rosacea.
  • Application to the eyelids (risk of glaucoma).
  • Application on the mucous membranes.
  • Do not apply to the breasts during breastfeeding, because of the risk of ingestion of the product by the newborn.

How To Take KENALCOL ?

Method of administration :

  • Place the tip of the spray bottle approximately 5 cm from the lesions to be treated.
  • Certain skin conditions make gradual cessation desirable. It can be obtained by reducing the frequency of applications and / or by using a less strong or less dosed corticosteroid.

how does KENALCOL work?

ASSOCIATION OF A DERMOCORTICOIDE OF MODERATE ACTIVITY, OF A KERATOLYTIC AND OF AN ANTISEPTIC.

(D: dermatology).

  • Topical corticosteroids are classified into 4 activity levels according to skin vasoconstriction tests: very strong, strong, moderate, weak activity.
  • Kenalcol, solution for skin application is a combination of a corticosteroid of moderate activity, a keratolytic and an antiseptic, benzalkonium chloride, of the quaternary ammonium class.
  • Triamcinolone acetonide is the essential active substance.
  • Active on certain inflammatory processes (for example: contact hypersensitivity) and the pruritic effect which is linked to them.

Vasoconstrictor.

  • By adding salicylic acid, the stratum corneum is more permeable to the corticosteroid. At the same time, the reservoir function of the stratum corneum decreases and higher corticosteroid concentrations are found in the dermis than with corticosteroid alone.

KENALCOL Side Effects

Redness, burning sensation after application.

Due to the presence of a corticosteroid :

  • The prolonged use of corticosteroids of moderate activity can cause skin atrophy, telangiectasias (to be feared particularly on the face), stretch marks (at the root of the limbs in particular, and occurring more readily in adolescents), ecchymotic purpura secondary to atrophy, skin fragility.
  • On the face, corticosteroids can create perioral dermatitis or worsen rosacea (see contraindications, warnings and precautions for use).
  • A delay in healing of sluggish wounds, bedsores, leg ulcers may be observed (see contraindications).
  • Possibility of systemic effects (see warnings and precautions for use: cushingoid syndrome, growth retardation, acute adrenal insufficiency).
  • Acneiform or pustular eruptions, hypertrichosis, depigmentations have been reported.
  • Secondary infections, particularly under an occlusive dressing or in the folds, and allergic contact dermatoses have also been reported during the use of local corticosteroids.

KENALCOL Interactions

  • Systemic intake of salicylates and topical application containing salicylic acid should be avoided while using this medication.
  • Not applicable.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

WARNINGS

  • Prolonged use on the face of corticosteroids of very strong, strong or moderate activity exposes the occurrence of corticosteroid-induced dermatitis and, paradoxically, corticosteroid, with rebound after each stop. A gradual weaning, particularly difficult, is then necessary.
  • Due to the passage of the corticosteroid into the systemic circulation, treatment over large areas or under occlusion may cause the systemic effects of systemic corticosteroid therapy, particularly in infants and toddlers. They consist of a cushingoid syndrome and a slowing of growth. These accidents disappear when treatment is stopped, but abrupt cessation can be followed by acute adrenal insufficiency.
  • Under the same conditions, salicylic acid can be responsible for salicylic intoxication.

PRECAUTIONS FOR USE

  • In infants, it is preferable to avoid corticosteroids of very strong, strong or moderate activity. One should be particularly wary of spontaneous occlusion phenomena which may occur in folds or under layers.
  • This medication should be used with caution, especially in children, in all circumstances likely to favor a systemic passage.
  • In the event of renal insufficiency, the treatment of a skin affection of great extent requires special monitoring because of the possible effects caused by the transcutaneous absorption of salicylic acid.
  •  In the event of bacterial or mycotic infection of a corticosensitive dermatosis, precede the use of the corticosteroid with a specific treatment.
  •  If a local intolerance appears, the treatment must be interrupted and the cause must be sought.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • No teratogenicity studies have been performed with topical corticosteroids.
  • However, studies concerning the intake of oral corticosteroids have not revealed a higher risk of malformation than that observed in the general population.
  • Therefore, this medication can be prescribed during pregnancy if needed.

Breastfeeding

  • Do not apply to the breasts during breastfeeding, because of the risk of ingestion of the product by the newborn.

What happens if I overdose from KENALCOL ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What should I do if I miss a dose?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking KENALCOL ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Lack of information in the MA.
  • 25 ml yellow (brown) glass bottle with acetal resin low density polyethylene (LDPE) metering pump.

Composition-


Solution for skin application
Active ingredient

Triamcinolone

  • 0.178 g *

Salicylic acid

  • 1.78 g *

Benzalkonium chloride

  • 0.089 g ** per unit dose

Active ingredients: Triamcinolone , Salicylic acid , Benzalkonium chloride

Excipients: Purified water , Alcohol

No excipient with known effect is not present in the composition of this drug

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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humoxal solution nasale Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1683/humoxal.html https://edrug-online.com/1683/humoxal.html#respond Sun, 22 Nov 2020 09:39:37 +0000 https://edrug-online.com/?p=1683 HUMOXAL, nasal solution, 15 ml vialGeneric drug of the Therapeutic class: Dermatology Active ingredients: Phenylephrine, Benzalkonium chloride Medicinal product withdrawn from the market on 02/20/2018 what is humoxal medication used for and indication? It is indicated as a short-term local adjunct treatment, antibacterial and decongestant, in rhinitis, sinusitis and nasopharyngitis in adults and adolescents over 15 years. PRESENTATION (S) AVAILABLE FOR HUMOXAL […]]]> HUMOXAL, nasal solution, 15 ml vial

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Phenylephrine, Benzalkonium chloride

Medicinal product withdrawn from the market on 02/20/2018

what is humoxal medication used for and indication?

It is indicated as a short-term local adjunct treatment, antibacterial and decongestant, in rhinitis, sinusitis and nasopharyngitis in adults and adolescents over 15 years.

PRESENTATION (S) AVAILABLE FOR HUMOXAL

2 presentations are available for this medication:

  • 1 glass spray bottle (s) of 10 ml with polypropylene dosing pump (s)
  • 1 glass spray bottle (s) of 15 ml with dosing pump
FEATURE DESCRIPTION
Pharmaceutical class nasal preparations
Active substance (s) per 100 ml: phenylephrine (hydrochloride) (0.250 g), benzalkonium (chloride) (0.040 g)
General medicine no
Pharmaceutical form solution
Route (s) of administration nasal
Selling price unregulated price
Social security reimbursement rate 0%
Laboratory (s) Laboratory (s) manufacturer Humoxal
Conditions of issue available by simple prescription

humoxal Dosage

  • RESERVED FOR ADULTS and ADOLESCENTS OVER 15 YEARS OLD.
  • Adults and adolescents over 15 years: 1 spray in each nostril, 3 to 5 times a day.
  • IN ALL CASES, FOLLOW YOUR DOCTOR’S ORDER.
  • If you have the impression that the effect of ANACORYL nasal solution is too strong or too weak, talk to your doctor or pharmacist.

humoxal Contraindications

Never use HUMOXAL, nasal solution in the following cases:

  • In case of known allergy to any of the constituents of this medication.
  • Child under 15 years old.
  • If you have had a stroke.
  • In case of severe arterial hypertension or not well balanced by the treatment.
  • In case of severe heart disease (coronary insufficiency).
  • If you have certain forms of glaucoma (increased pressure in the eye).
  • In case of difficulty urinating of prostatic or other origin.
  • In case of old or recent convulsions.
  • If you are breast-feeding.
  • In combination with non-selective MAOIs due to the risk of paroxysmal hypertension and hyperthermia which can be fatal.
  • In combination with other sympathomimetics with indirect action, vasoconstrictors intended to decongest the nose whether they are administered orally or nasally [phenylephrine (aka neosynephrine), pseudoephedrine, ephedrine, etc.] and methylphenidate because of the risk of vasoconstriction and / or flare-ups hypertensive.
  • In combination with alpha-type sympathomimetics, vasoconstrictors intended to decongest the nose whether administered orally or nasally [etilefrin, midodrine, naphazoline, oxymetazoline, phenylephrine, synephrine, tetryzoline, tuaminoheptane, tymazoline] because of the risk of vasoconstriction and / or hypertensive outbreaks.

The combination of two decongestants is contraindicated, whatever the route of administration (oral and / or nasal): such a combination is unnecessary and dangerous and corresponds to misuse.

You should generally not use this medicine, unless your doctor tells you otherwise, during pregnancy.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

How To Take humoxal ?

Method and route of administration

  • Nasal sprays are done with the bottle in an upright position, with the head tilted slightly forward, to avoid swallowing the product.
  • Before first use, prime the dosing pump by pressing several times sharply outside the nostril.
  • Insert the end of the nasal nozzle into the nostril after removing its protective cap and press as shown in the diagram below.

Duration of treatment

  • The maximum duration is 3 to 5 days.

how does humoxal work?

  • SYMPATHOMIMETICS IN ASSOCIATION EXCEPT CORTICOIDS, ATC Code: R01AB01
  • This medication is a combination of an indirect sympathomimetic, vasoconstrictor, decongestant by the nasal route and an antiseptic, benzalkonium chloride.

How To Store humoxal ?

Keep out of the reach and sight of children.

Expiration date

  • Do not use HUMOXAL, nasal solution after the expiry date stated on the bottle. The expiration date refers to the last day of the month.

Storage conditions

  • No special storage conditions.

humoxal Side Effects

Like all medicines, HUMOXAL nasal solution can cause side effects, although not everybody gets them.

This medicine can cause:

Linked to the presence of phenylephrine

Local effects:

  • phenomena of nasal dryness may occur in some patients and exceptionally, local allergic manifestations.

General effects such as:

  • headaches, strokes,
  • palpitations, high blood pressure, myocardial infarction, sweating, behavioral disturbances, nausea, vomiting,
  • the onset of an acute glaucoma attack in susceptible subjects, which can result in a red and painful eye.

IN THESE CASES, STOP THE TREATMENT AND CONTACT YOUR DOCTOR IMMEDIATELY.

Can also occur:

  • urinary disorders (significant decrease in urine, difficulty in urinating),
  • dry mouth
  • convulsions, hallucinations, agitation, behavioral disturbances and insomnia have been described,
  • exceptionally, hemorrhagic cerebrovascular accidents have been reported in patients treated with medicinal products containing a vasoconstrictor, in particular in the event of overdose, non-compliance with contraindications or warnings, or in patients presenting vascular risk factors.

If you notice any side effects not mentioned in this leaflet, please tell your doctor or pharmacist.

Keep out of the reach and sight of children.

humoxal Interactions

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

This medication contains a vasoconstrictor: phenylephrine.

This medicine must not be administered in combination with:

  • other vasoconstrictors, whether administered orally or nasally (phenylephrine (alias neosynephrine), pseudoephedrine, ephedrine, methylphenidate, etilefrin, midodrine, naphazoline, oxymetazoline, phenylephrine, synephrine, tetryzoline, tuaminoheptane),
  • a non-selective MAOI (iproniazid).

It is not recommended to use this medicine if you are already being treated:

  • by a selective MAO-A drug, a drug prescribed in certain depressive states;
  • and / or by other dopaminergic or vasoconstrictor drugs such as bromocriptine, cabergoline, lisuride, pergolide or dihydroergotamine, ergotamine, methylergometrine, methysergide, drugs prescribed to treat certain neurological or endocrine disorders or migraines ;
  • with linezolid

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

Special warnings

Follow the instructions for use and the doses recommended in this leaflet.

Do not swallow.

From the opening of the packaging, and a fortiori from the first use of a preparation for nasal use, microbial contamination is possible. Do not keep an opened preparation for nasal use for too long, in particular do not reuse it for another treatment.

DO NOT LEAVE THIS MEDICINAL PRODUCT IN THE REACH OR SIGHT OF CHILDREN.

It is imperative to strictly observe the dosage, the maximum duration of treatment of 3 to 5 days and the contraindications.

During the treatment, in case of sensation of acceleration of the heartbeat, palpitations, appearance or increase of headaches, appearance of nausea, behavioral disturbances,

STOP TREATMENT AND CONTACT YOUR DOCTOR IMMEDIATELY.

TELL YOUR DOCTOR if you suffer from:

  • high blood pressure,
  • heart disease, hyperthyroidism (hyperfunction of the thyroid gland),
  • personality disorders,
  • of diabetes.

TELL YOUR DOCTOR if you are taking:

  • a selective MAO-A (moclobemide, toloxatone)
  • a treatment containing a rye ergot alkaloid:
    • dopaminergic, such as bromocriptine, cabergoline, lisuride or pergolide, (eg an antiparkinsonian);
    • vasoconstrictor, such as dihydroergotamine, ergotamine, methylergometrine, methysergide), (eg an anti-migraine medication);
  • linezolid.

In case of purulent nasal discharge, persistent fever, no improvement after 3 to 5 days of treatment, CONSULT YOUR DOCTOR.

Related to the presence of benzalkonium chloride

Due to the presence of benzalkonium chloride, this medication may cause breathing difficulties.

IF IN DOUBT, DO NOT HESITATE TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • Clinically, epidemiological studies have not revealed any malformative effect linked to the use of phenylephrine. However, as a precaution and given the potent vasoconstrictor properties of this drug, it is best not to use it during pregnancy. However, in the event of administration, the prescription will be made in accordance with the recommended dosage and duration of administration.

Feeding with milk

  • There are no data concerning the passage of phenylephrine in breast milk. In view of the vasoconstrictor properties of phenylephrine and the possible occurrence of cardiovascular and neurological effects in infants, the intake of this drug is contraindicated during breast-feeding.

What happens if I overdose from humoxal ?

In case of repeated or abusive administration, phenylephrine can cause, by systemic passage: hypothermia, sedation, loss of consciousness, coma or respiratory depression.

What should I do if I miss a dose?

If you forget to take HUMOXAL, nasal solution:

  • Do not use a double dose to make up for the dose you forgot to use. Continue your treatment as prescribed.

What happens if you stop taking humoxal ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Lack of information in the MA.
  • 15 ml in spray bottle (glass) with dosing pump (polypropylene).

Composition

Nasal solution Active ingredient

Benzalkonium chloride

0.04 g *

Phenylephrine

0.25 g * * per unit dose

Active ingredients: Benzalkonium chloride , Phenylephrine

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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Celestoderm cream Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1754/celestoderm-cream.html https://edrug-online.com/1754/celestoderm-cream.html#respond Sun, 22 Nov 2020 09:38:52 +0000 https://edrug-online.com/?p=1754 Celestoderm RelaisGeneric drug of the Therapeutic class: Dermatology Active ingredients:  Betamethasone Medicinal product withdrawn from the market on 05/23/2012 what is celestoderm medication used for and indication? Celestoderm cream is more particularly intended for acute, oozing lesions Celestoderm Relais is intended for relaying corticosteroids of stronger activity. Preferred indications where local corticosteroid therapy is considered the best treatment: […]]]> Celestoderm Relais

Generic drug of the Therapeutic class: Dermatology
Active ingredients:  Betamethasone

Medicinal product withdrawn from the market on 05/23/2012

what is celestoderm medication used for and indication?

Celestoderm cream is more particularly intended for acute, oozing lesions

Celestoderm Relais is intended for relaying corticosteroids of stronger activity.

  1. Preferred indications where local corticosteroid therapy is considered the best treatment:
    • contact eczema,
    • atopic dermatitis.
  2. Indications where local corticosteroid therapy is one of the usual treatments :
    • stasis dermatitis,
    • relay psoriasis, in folds or in children,
    • seborrheic dermatitis.
  3. Indications of circumstance for a short period :
    • insect bites and parasitic prurigo after etiological treatment.
    • Note: each dermatosis must be treated with a corticosteroid of the most appropriate level, knowing that depending on the results, it may be necessary to substitute a product with a stronger or weaker activity on all or part of the lesions.

celestoderm Dosage

  • Treatment should be limited to 1 to 2 applications per day.
  • An increase in the number of daily applications may worsen the side effects without improving the therapeutic effects.
  • The treatment of large surfaces requires monitoring the number of tubes used.
  • It is advisable to apply the product in spaced strokes, then to spread it by massaging lightly until it is fully absorbed.
  • Certain dermatoses (psoriasis, atopic dermatitis, etc.) make gradual cessation desirable. It can be obtained by reducing the frequency of applications and / or by using a less strong or less dosed corticosteroid.

celestoderm Contraindications

Never use CELESTODERM RELAIS 0.05 PER CENT, cream in the following cases:

  • allergy to any component of the drug
  • ulcerated lesions
  • acne
  • rosacea
  • infectious diseases of the skin of viral (herpes, shingles, chickenpox …), bacterial (example: impetigo …), mycotic (due to microscopic fungi) or parasitic origin.
  • application to the eyelids.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

how does celestoderm work?

DERMOCORTICOIDE.

(D: Dermatology).

  • Topical corticosteroids are classified into 4 activity levels according to skin vasoconstriction tests: very strong, strong, moderate, weak activity.
  • Célestoderm Relais cream is moderately active.
  • Active on certain inflammatory processes (for example: contact hypersensitivity) and the pruritic effect which is linked to them.
  • Vasoconstrictor. Inhibits cell multiplication.

How To Store celestoderm ?

Keep out of the reach and sight of children.

Expiration date

  • Do not use CELESTODERM RELAIS 0.05 PERCENT, cream after the expiry date stated on the box. The expiration date refers to the last day of the month.

Storage conditions

  • No special storage conditions.

celestoderm Side Effects

  • The prolonged use of corticosteroids of strong activity can lead to atrophy of the skin, telangiectasias (to be feared particularly on the face), stretch marks (at the root of the limbs in particular, and occurring more readily in adolescents), ecchymotic purpura secondary to atrophy, skin fragility.
  • On the face, corticosteroids can create perioral dermatitis or worsen rosacea (see contraindications, warnings and precautions for use).
  •  A delay in healing of sluggish wounds, bedsores, leg ulcers may be observed (see contraindications).
  •  Possibility of systemic effects (see warnings: cushingoid syndrome, growth retardation, acute adrenal insufficiency).
  • Acneiform or pustular eruptions, hypertrichosis, depigmentations have been reported.
  • Secondary infections, particularly under occlusive dressings or in the folds, and allergic contact dermatoses have also been reported with the use of local corticosteroids.

celestoderm Interactions

Interactions with other drugs

Taking or using other medicines

  • Considering local use of this product: At recommended doses, betamethasone for topical use is not likely to cause medically significant drug interactions.
  • If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Interactions with food and drink

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Interactions with phytotherapy products or alternative therapies

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

Take special care with CELESTODERM RELAIS 0.05 PERCENT, cream:

Precautions for use

This medication should be used in accordance with the doctor’s advice:

  • ·do not apply to the face except in the event of a formal prescription from your doctor,
  • ·avoid applications over a large area, under an occlusive dressing because of the possibility of part of the active principle passing into the blood,
  • ·avoid prolonged application, on the face, in the folds,
  • ·any irritation or infection should be reported to your doctor,
  • ·if an intolerance reaction appears, the treatment should be stopped.

This medicine contains chlorocresol and may cause allergic reactions.

This medicine contains cetostearyl alcohol and may cause local skin reactions (eg eczema).

IN CASE OF DOUBT, DO NOT HESITATE TO ASK YOUR DOCTOR OR YOUR PHARMACIST FOR ADVICE.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • No teratogenicity studies have been performed with topical corticosteroids.
  • However, studies concerning the intake of oral corticosteroids have not revealed a higher risk of malformation than that observed in the general population.

Breast-feeding

  • During oral treatment, breast-feeding should be avoided because corticosteroids are excreted in breast milk.

What happens if I overdose from celestoderm ?

If you used more CELESTODERM RELAIS 0.05 PERCENT, cream than you should:

Always use CELESTODERM RELAIS 0.05 PERCENT, cream as your doctor has told you. If you accidentally applied more CELESTODERM RELAIS 0.05 PERCENT, cream than prescribed by your doctor, do not worry but avoid reproducing it. Excessive or prolonged use of topical corticosteroids can cause manifestations of hypercorticism, including Cushing’s disease.

Treatment: Appropriate symptomatic treatment is indicated.

What should I do if I miss a dose?

If you forget to use CELESTODERM RELAIS 0.05 PERCENT, cream:

Do not apply a double dose to make up for the dose you forgot to apply.

What happens if you stop taking celestoderm ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Lack of information in the MA.
  • 25 g tube (painted aluminum).

Composition

Active ingredient Cream : Betamethasone 50 mg ** per unit dose

  • Active ingredients: Betamethasone
  • Excipients with known effects ? : Cetostearyl alcohol
  • Other excipients: Chlorocresol, Macrogol monocetyl ether 1000, Vaseline, Liquid paraffin, Sodium dihydrogenphosphate monohydrate, Concentrated phosphoric acid, Purified water

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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Daivonex ointment Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1934/daivonex-ointment.html https://edrug-online.com/1934/daivonex-ointment.html#respond Wed, 18 Nov 2020 10:34:21 +0000 https://edrug-online.com/?p=1934 DAIVONEX 50 micrograms / gram, ointmentDAIVONEX 50 micrograms / gram, ointment >>> Generic drug of the Therapeutic class: Dermatology Active ingredients: Calcipotriol what is Daivonex ointment used for and indication? This medication is a cream for topical application containing a derivative of vitamin D. It is recommended in the treatment of psoriasis. PRESENTATION (S) AVAILABLE FOR DAIVONEX 50 ΜG / […]]]> DAIVONEX 50 micrograms / gram, ointment

DAIVONEX 50 micrograms / gram, ointment >>> Generic drug of the Therapeutic class: Dermatology
Active ingredients: Calcipotriol

what is Daivonex ointment used for and indication?

This medication is a cream for topical application containing a derivative of vitamin D.

It is recommended in the treatment of psoriasis.

PRESENTATION (S) AVAILABLE FOR DAIVONEX 50 ΜG / GRAM

3 presentations are available for this drug:

  • 1 painted aluminum tube (s) of 30 g
  • 1 tube (s) painted aluminum of 100 g
  • 1 120 g painted aluminum tube (s)
FEATURE DESCRIPTION
Pharmaceutical class psoriasis treatment
Active substance (s) calcipotriol monohydrate
General medicine no
Pharmaceutical form cream
Route (s) of administration cutaneous
Social security reimbursement rate 65%
Laboratory (s) LEO
Conditions of issue available by simple prescription

Daivonex Dosage

  • An application morning and evening to the lesions. In maintenance treatment and depending on the results, the frequency of applications may be reduced to once a day.
  • The maximum dose to apply is 100 g of cream per week.
  • In the event of concomitant use of DAIVONEX ointment, this maximum dose of 100 g per week should take into account the amount of ointment used.
  • Calcipotriol cream can be usefully combined with local corticosteroids, and in more widespread forms of psoriasis, with phototherapy, ciclosporin or acitretin, respecting the maximum dose of 100 g of cream per week and, in applying to a body surface area of ​​less than 40%.
  • If combined with topical corticosteroids, one of the treatments will be applied in the morning, the other in the evening.
  • In children, clinical efficacy and safety data are very limited. In clinical studies DAIVONEX was only used in 79 children aged 6 to 12 years and 19 children over 12 years of age for 6 to 8 weeks. The average dose applied per week (approximately 15 grams) was often lower than the maximum dose allowed in clinical studies (50 grams for the age of 6 to 12 years and 75 grams for the age of 12 to 16 years). Under these conditions, the treatment was well tolerated.
  • The possible impact on bone growth from prolonged treatment with topical calcipotriol is not known.

Daivonex Contraindications

Never use DAIVONEX 50 micrograms / gram, cream in case of:

CONTRA-INDICATED:

  • History of allergy to calcipotriol or to one of the excipients.
  • Hypercalcemia whatever the origin.
  • The cream should not be applied to the face.

ADVISED AGAINST:

  • In the absence of clinical data, the use of calcipotriol in other forms of psoriasis is not recommended (pustular, gouty, erythrodermic psoriasis).
  • Breast-feeding: it is not known whether calcipotriol passes into breast milk.

How To Take Daivonex ?

Administration mode

  • Dermal.

Frequency of administration

  • For best results, apply the cream twice a day, once in the morning and once in the evening.
  • Depending on the results, your doctor may instruct you to apply the cream only once a day.

how does Daivonex work?

Pharmacotherapeutic group: OTHER MEDICINAL PRODUCTS AGAINST PSORIASIS FOR TOPICAL USE, ATC code: D05AX02.

Calcipotriol is a structural analogue of vitamin D. Calcipotriol allows differentiation and inhibits the proliferation of keratinocytes in vitro, thus correcting the abnormality of these cells observed during psoriasis.

How To Store Daivonex ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month. The tube should be discarded 6 months after first use.
  • Store the tube at a temperature not exceeding 25 ° C.
  • Do not freeze.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

Daivonex Side Effects

Like all medicines, DAIVONEX 50 micrograms / gram, cream can cause side effects, although not everybody gets them:

  • Skin irritation may occur in the lesions treated, usually not requiring discontinuation of treatment; If the irritation persists, report it to your doctor.
  • Possibility of skin irritation on the face: this should not occur if the hands are washed properly after application.
  • If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
  • Keep out of the reach and sight of children.

Daivonex Ointment Interactions

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

daivonex ointment Warnings and Precautions

Special warnings

  • Do not apply under an occlusive dressing, or in the folds without first consulting your doctor.
  • IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

Precautions for use

  • Do not apply on the face. Applying DAIVONEX 50 micrograms / gram, cream to the face may cause local irritation. Wash hands after each use to avoid accidental transfer to the face or mouth.
  • Do not exceed the maximum dose prescribed by your doctor.
  • Avoid excessive exposure to natural or artificial light and any other form of treatment with light rays.
  • If in doubt, do not hesitate to seek the advice of your doctor or pharmacist.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • There are no data from the use of calcipotriol in pregnant women.
  • Oral animal studies have shown reproductive toxicity.
  • Daivonex should not be used during pregnancy unless clearly necessary.

Feeding with milk

  • There are no data on the excretion of calcipotriol in human milk.
  • Caution should be exercised when prescribing Daivonex to breast-feeding women. The patient should be instructed not to use Daivonex on the breasts while breastfeeding.

Fertility

  • Studies in rats have shown no impairment of fertility in males and females after oral administration of calcipotriol.

What happens if I overdose from Daivonex ?

Immediately consult your doctor or pharmacist.

What should I do if I miss a dose?

Do NOT apply a double dose to make up for the dose you forgot to apply.

What happens if you stop taking Daivonex ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

SHAPES and PRESENTATIONS

  • Ointment.
  • 120 g painted aluminum tube.

Other shapes

  • DAIVONEX 50 micrograms / gram, cream, 30 g tube
  • DAIVONEX 50 micrograms per ml, solution for scalp, 60 ml vial
  • DAIVONEX 50 micrograms / gram, ointment, 30 g tube
  • DAIVONEX 50 micrograms / gram, cream, 120 g tube
  • DAIVONEX 50 micrograms per ml, solution for scalp, 120 ml vial

COMPOSITION


p 100 g
Calcipotriol (as calcipotriol monohydrate) 0.005 g
  • Excipients: sodium edetate, sodium hydrogenphosphate dihydrate, liquid paraffin (containing all-rac-alpha-tocopherol), petrolatum (containing all-rac-alpha-tocopherol), 85 percent glycerol, ketostearyl ether macrogol, alcohol cetostearyl, diazolidinyl urea, 2,4-dichlorobenzyl alcohol, sodium hydroxide (for pH adjustment), purified water.
  • Excipients with known effect: Each g of cream contains 72 mg of cetostearyl alcohol, 1 mg of dichloro -2.4 benzyl alcohol, and 3 mg of diazolidinyl urea.

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
]]>
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daivobet gel Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1747/daivobet-gel.html https://edrug-online.com/1747/daivobet-gel.html#respond Tue, 17 Nov 2020 10:27:41 +0000 https://edrug-online.com/?p=1747 How do you use daivobet gelGeneric drug of the Therapeutic class: Dermatology Active ingredients: Calcipotriol , Betamethasone what is daivobet gel medication used for and indication? Daivobet is used as a topical treatment for scalp psoriasis in adults and mild to moderate psoriasis (psoriasis vulgaris) patches in the rest of the body in adults. Psoriasis is caused by your skin cells being produced too quickly. This […]]]> How do you use daivobet gel

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Calcipotriol , Betamethasone

what is daivobet gel medication used for and indication?

Daivobet is used as a topical treatment for scalp psoriasis in adults and mild to moderate psoriasis (psoriasis vulgaris) patches in the rest of the body in adults. Psoriasis is caused by your skin cells being produced too quickly. This causes redness, peeling and thickening of the skin.

Daivobet contains calcipotriol and betamethasoneCalcipotriol helps restore the rate of growth of skin cells to normal, and betamethasone works by reducing inflammation.

PRESENTATION (S) AVAILABLE FOR DAIVOBET 50 ΜG / 0.5 MG / G

5 presentations are available for this drug:

  • 1 bottle (s) high density polyethylene (HDPE) of 15 g
  • 1 bottle (s) high density polyethylene (HDPE) of 30 g
  • 1 bottle (s) high density polyethylene (HDPE) of 60 g
  • 2 high density polyethylene (HDPE) bottle (s) of 60 g
  • 3 high density polyethylene (HDPE) bottle (s) of 60 g
FEATURE DESCRIPTION
Pharmaceutical class psoriasis treatment
Active substance (s) betamethasone dipropionate, calcipotriol monohydrate
General medicine no
Pharmaceutical form gel
Route (s) of administration cutaneous
Social security reimbursement rate 65%
Laboratory (s) LEO
Conditions of issue available by simple prescription

daivobet gel Dosage

Always take the dose recommended by your doctor. If in doubt, consult your doctor or pharmacist.

How to apply Daivobet

  • Cutaneous use.

Instruction for correct use

  • Apply the product only to psoriasis and not to skin that does not have psoriasis.
  • Shake the bottle before use and remove the cap
  • Put gel on a clean finger or directly on the areas affected by psoriasis.
  • Apply Daivobet to the area affected by psoriasis with your fingertip and work it in by rubbing gently until this area is covered by a thin layer of gel.
  • Do not cover the treated area with neither a bandage nor a tight bandage
  • Wash hands thoroughly after using Daivobet. This will prevent accidental transfer of gel to other parts of the body (especially on the face, mouth and eyes)
  • Don’t worry if you accidentally apply the gel to healthy skin around the psoriasis lesions, but wipe it off if it spreads too widely
  • For optimal effect, it is recommended not to shower or bathe immediately after application of Daivobet gel.
  • After applying the gel, avoid contact with fabrics that are easily stained with grease (such as silk).

If you have scalp psoriasis

  • Before applying Daivobet to the scalp, first style your hair to eliminate dandruff. Tilt your head to make sure Daivobetdoes not run on your face. Making a line can facilitate the application of Daivobet. Apply Daivobet to the affected area with your fingertip and rub it in gently.
  • For the treatment of the scalp, usually an amount between 1 and 4 g is sufficient to treat the scalp (4 g corresponds to a teaspoon)
  • Washing your hair before applying Daivobet is not necessary
  • For optimum effect, it is recommended not to wash your hair immediately after applying Daivobet. Leave Daivobet in contact with the scalp overnight or during the day.

Duration of the treatment

  • Use the gel once a day. It may be more convenient to apply the gel in the evening
  • The normal initial treatment period is 4 weeks for the scalp and 8 weeks outside the scalp.
  • Your doctor may prescribe a different duration of treatment.
  • Your doctor may decide to repeat the treatment.
  • Do not use more than 15 grams per day.

If you are using other products containing calcipotriol, the total calcipotriol should not exceed 15 grams per day and the treated area should not exceed 30% of the total body surface.

What should I expect from my treatment with Daivobet

Most patients see a clear result after 2 weeks even if the psoriasis has not completely gone away.

daivobet gel Contraindications

Never use Daivobet:

  • If you are allergic (hypersensitive) to calcipotriol, betamethasone or any of the other ingredients of Daivobet.
  • If you have problems with calcium levels in the body (ask your doctor).
  • If you have psoriasis of a certain type: such as gouty, erythrodermic, exfoliating, or pustular psoriasis (ask your doctor).
  • If you have severe liver or kidney disease.

As Daivobet contains a strong corticosteroid, do NOT use it on skin with

  • infection caused by a virus (such as a cold sore or chickenpox)
  • infection caused by a fungus (athlete’s foot or ringworm),
  • infection caused by bacteria,
  • infection caused by a parasite (such as gall),
  • tuberculosis or syphilis,
  • perioral dermatitis (redness around the mouth),
  • thinning of the skin, easily damaged veins, stretch marks,
  • ichthyosis (dry skin with kinds of scales),
  • acne (pimples),
  • rosacea (sudden severe redness or redness of the skin of the face),
  • ulcers or rupture of the skin barrier,
  • itching of the anus (rectum) or genitals (sexual organs).

how does daivobet gel work?

Pharmacotherapeutic group: Antipsoriatics; other antipsoriatics for topical use – calcipotriol in combination (ATC code: D05AX52).

Calcipotriol is an analogue of vitamin D. In vitro data suggest that calcipotriol induces differentiation and inhibits the proliferation of keratinocytes. This is the mechanism proposed to explain its effects in psoriasis.

Like other topical corticosteroids, betamethasone dipropionate has anti-inflammatory, antipruritic, vasoconstrictive, and immunosuppressive properties, however, with no demonstrated curative action. Treatment under occlusion may increase the effect due to greater penetration into the stratum corneum. The incidence of side effects will therefore be increased. In general, the mechanism of action of the anti-inflammatory activity of topical corticosteroids is not fully understood.

The adrenal response to ACTH was determined by measuring cortisol in patients with both extensive scalp and body psoriasis using up to 106 g per week of Daivobet gel in combination with Daivobet ointment. A borderline decrease in cortisol levels 30 minutes after ACTH administration was observed in 5 of 32 patients (15.6%) after 4 weeks of treatment and in 2 of 11 patients (18.2%) who had prolonged treatment up to 8 weeks. In all cases, cortisol levels were at a normal level 60 minutes after the administration of ACTH. No changes in calcium metabolism were observed in these patients. Regarding hypothalamic-pituitary braking, this study demonstrates that

The efficacy of once-daily use of Daivobet gel has been evaluated in two randomized, double-blind, 8-week clinical studies including a total of over 2900 patients with scalp psoriasis of at least severity mild according to the Investigator’s Global Assessment of Disease Severity (IGA). The comparators were betamethasone dipropionate in the gel vehicle, calcipotriol in the gel vehicle, and (in one of the studies) the gel vehicle alone, all used once daily. Results for the primary endpoint (absence of disease or very slight presence of disease according to IGA at week 8) showed that Daivobet gel was significantly more effective than the comparators. The results on the speed of

% of patients with absence of disease or very slight presence of disease week 2 week 8
Daivobet gel (n = 1108) 53.2% 69.8%
Betamethasone dipropionate (n = 1118) 42.8% (1) 62.5% (1)
Calcipotriol (n = 558) 17.2% (1) 40.1% (1)
Freeze vehicle (n = 136) 11.8% (1) 22.8% (1)

(1)   Statistically less effective than Daivobet gel (p <0.001).

The effectiveness of Daivobet gel used once daily on the body (excluding the scalp) was evaluated in a randomized, double-blind, 8-week clinical study which included 296 patients with psoriasis vulgaris of mild or severe severity. moderate according to the IGA. The comparators were betamethasone dipropionate in the gel vehicle, calcipotriol in the gel vehicle, and the gel vehicle alone, all used once daily. The primary response criteria were IGA controlled disease at week 4 and week 8. Controlled disease was defined as “bleached” or “minimally impaired” for patients with moderate disease at T0 or “bleached” for patients with mild disease at T0.

The secondary response endpoints were percentage change in Psoriasis Severity and Area index (PASI) between T0 and week 4 and between T0 and week 8.

% of patients with controlled disease week 4 week 8
Daivobet gel (n = 126) 20.6% 31.7%
Betamethasone dipropionate (n = 68) 10.3% (1) 19.1% (1)
Calcipotriol (n = 67) 4.5% (1) 13.4% (1)
Freeze vehicle (n = 35) 2.9% (1) 0.0% (1)

(1)   Statistically less effective than Daivobet gel (p <0.05).

Average percentage reduction in PASI (DS) week 4 week 8
Daivobet gel (n = 126) 50.2 (32.7) 58.8 (32.4)
Betamethasone dipropionate (n = 68) 40.8 (33.3) (1) 51.8 (35.0)
Calcipotriol (n = 67) 32.1 (23.6) (1) 40.8 (31.9) (1)
Freeze vehicle (n = 35) 17.0 (31.8) (1) 11.1 (29.5) (1)

(1)   Statistically less effective than Daivobet gel (p <0.05).

Another randomized, single-blind, clinical study including 312 patients with scalp psoriasis of at least moderate severity according to the IGA investigated the use of Daivobet gel once daily compared with that of Daivonex scalp solution two. times a day for 8 weeks. Results for the primary endpoint (absence of disease or very mild disease presence according to IGA at week 8) showed that Daivobet gel was statistically more effective than Daivonex scalp solution.

% of patients with absence of disease or very slight presence of disease week 8
Daivobet gel (n = 207) 68.6%
Daivonex scalp solution (n = 105) 31.4% (1)

(1)   Statistically less effective than Daivobet gel (p <0.001).

A long-term, randomized, double-blind clinical study including 873 patients with scalp psoriasis of at least moderate severity at baseline (according to IGA) investigated the use of Daivobet gel in comparison with that of calcipotriol in the vehicle of the gel. Both treatments were applied once daily, intermittently as needed, for up to 52 weeks. Adverse effects, possibly related to the long-term use of corticosteroids on the scalp, have been identified blindly by an independent panel of dermatologists. There was no difference in the percentage of patients with such adverse effects between the treated groups (2.6% in the Daivobet gel group and 3.0% in the calcipotriol group; p = 0.73). No case of skin atrophy

Pediatric population:

Scalp :

The effects on calcium metabolism were investigated in 2 open-label, uncontrolled 8-week clinical trials including a total of 109 adolescents aged 12 to 17 years with scalp psoriasis, using up to 69 g per week of Daivobet gel. No cases of hypercalcaemia and no clinically relevant changes in calciuria have been reported. The adrenal response to the administration of ACTH was measured in 30 patients; one patient showed a slight decrease in his cortisol levels on administration of ACTH after 4 weeks of treatment, without clinical manifestation and reversible.

Scalp and body:

The effects on calcium metabolism were studied in an 8-week, open-label, uncontrolled clinical trial in 107 adolescents aged 12 to 17 years with psoriasis of the scalp and body, using up to 114.2 g per Daivobet gel week. No cases of hypercalcaemia and no clinically relevant changes in calciuria have been reported. The adrenal response to the ATCH test was measured in 31 patients; the response to cortisol was decreased after the ACTH test in 5 patients of which 2 patients showed only a limited decrease. This decrease was observed after 4 weeks of treatment in 4 patients, and after 8 weeks of treatment in 2 patients including 1 patient who showed a decrease in his cortisolemia after 4 and 8 weeks of treatment.

How To Store daivobet gel ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the bottle and the cartridge after EXP. The expiration date refers to the last day of that month.
  • Do not put in the refigerator.
  • Store in the outer packaging in order to protect from light.
  • The bottle should be discarded 6 months after first opening with the gel it contains.
  • The applicator is disposable. The applicator should be discarded 6 months after first opening with the gel it contains.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

daivobet gel Side Effects

Like all medicines, Daivobet can cause side effects, although not everybody gets them.

About 1 in 12 people may experience side effects, but most are reactions at the site of application of the gel.

Serious side effects:

Contact your doctor / nurse immediately or as soon as possible if any of these reactions occur. You may need to stop your treatment:

The following serious side effects have been reported for Daivobet

Rare (affect less than 1 in 100 people)

  • Worsening of your psoriasis. If your psoriasis gets worse, talk to your doctor as soon as possible.

Serious side effects are known to be caused by betamethasone (a strong corticosteroid), one of the ingredients of Daivobet gel. Tell your doctor as soon as possible if a serious side effect occurs. These side effects most often occur after prolonged use, or under occlusion. These effects include the following:

  • Your adrenal glands may stop working properly. The signs are fatigue, depression, and anxiety.
  • Cataract (signs are blurry and blurred vision, difficulty seeing at night, and sensitivity to light) or increased pressure in the eye (signs are eye pain, red eye, decreased vision or blurred vision ).
  • Infections (because your infection-fighting immune system may be weakened or weakened).
  • Pustular psoriasis (a red area with yellowish pustules usually on the hands or feet). If you notice it, stop taking Daivobet gel and talk to your doctor as soon as possible.
  • Impact on the control of the metabolism of diabetes mellitus (if you are diabetic you may have fluctuations in your blood sugar).

Serious side effects are known to be caused by calcipotriol:

  • Allergic reactions with severe swelling of the face or other parts of the body such as the hands or feet. Swelling of the lips and difficulty in breathing can happen. If you have an allergic reaction, stop using Daivobet gel, tell your doctor straight away, or go to the nearest hospital emergency room.
  • Treatment with this gel may increase your calcium levels in the blood or urine (usually when too much gel has been used). Signs of increased calcium in the blood are bone pain, constipation, loss of appetite, nausea, and vomiting. This can be serious and you should contact your doctor immediately. However, when treatment is stopped, the levels return to normal.

Less serious side effects:

The following less serious side effects have been reported with Daivobet:

Common side effects (affect less than 1 in 10 people)

  • Itching.

Uncommon side effects (affect less than 1 in 100 people):

  • Eye irritation.
  • Burning sensation of the skin.
  • Skin pain or irritation.
  • Inflammation or swelling of the hair roots (folliculitis).
  • Redness with inflammation of the skin (dermatitis).
  • Redness of the skin due to the dilation of small blood vessels (erythema).
  • Acne (pimples).
  • Dry skin.
  • Eruptions.
  • Rash of pustules.

Less serious side effects caused by betamethasone when used for a long time include the following side effects, and you should tell your doctor or nurse as soon as possible if you notice them:

  • Thinning of the skin.
  • Appearance of surface veins or stretch marks.
  • Change in hair growth.
  • Redness around the mouth (perioral dermatitis).
  • Red rash with inflammation and swelling (allergic contact dermatitis).
  • Small white buttons (colloid milium).
  • Depigmentation (lightening of the skin).

Other less serious side effects that have been reported include:

  • Sensitivity of the skin to light causing a rash.
  • Eczema.

If you notice the effects described above or other changes during treatment, tell your doctor.

If you experience any of the side effects listed as serious, or if you experience any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

Keep out of the reach and sight of children.

daivobet gel Interactions

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

Warnings and Precautions

Take special care with Daivobet

Before using this medicine, tell your doctor / nurse / pharmacist if:

  • you are taking other medicines which contain corticosteroids as you may have side effects
  • you have been taking this medicine for a long time and plan to stop the treatment (there is a risk that your psoriasis will get worse or ‘flare up’ when the corticosteroids are suddenly stopped),
  • you have diabetes (diabetes mellitus) because blood sugar / glucose levels may be affected by corticosteroids
  • your skin becomes infected because you may need to stop treatment.

Special precautions

  • Avoid using on more than 30% of your body or using more than 15 grams per day.
  • Avoid use under a shower cap, bandages or dressings as this increases the absorption of corticosteroids.
  • Avoid use on large areas of damaged skin or on skin folds (groin, under the arms, under the breasts) as this increases the absorption of corticosteroids.
  • Avoid use on the face or the genitals (sexual organs) as these are very sensitive to corticosteroids.
  • Avoid excessive exposure to the sun, excessive use of solar cabins, or other form of light therapy.

Children

  • Daivobet is not recommended for children and adolescents under the age of 18.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • There are no sufficiently good data from the use of Daivobet in pregnant women. Animal studies with glucocorticoids have shown reproductive toxicity ( see Preclinical Safety ), but a number of epidemiological studies (less than 300 pregnancies) have not shown congenital anomalies in patients. children born to mothers treated with corticosteroids during pregnancy. The potential risk for humans is not known for sure. Therefore, Daivobet should only be used during pregnancy when the potential benefit justifies the potential risk.

Feeding with milk

  • Betamethasone is excreted in human milk, but the risk of an adverse effect in the infant seems unlikely at therapeutic doses. There are no data on the excretion of calcipotriol in human milk. Caution should be exercised when prescribing Daivobet in nursing mothers. The patient should be instructed not to use Daivobet on the breasts while breastfeeding.

Fertility

  • Studies in rats after oral administration of calcipotriol or betamethasone dipropionate have shown no impairment of fertility in males and females ( see Preclinical Safety ).

What happens if I overdose from daivobet gel ?

  • The use of doses higher than the recommended dose may lead to an increase in serum calcium, this effect is reversible on discontinuation of treatment. Symptoms of hypercalcemia include polyuria, constipation, muscle weakness, confusion, and coma.
  • Excessive and prolonged use of topical corticosteroids can lead to hypothalamic-pituitary axis slowing, resulting in secondary adrenal insufficiency which is usually reversible. In this case, symptomatic treatment is indicated.
  • In the event of chronic toxicity, treatment with corticosteroids should be withdrawn gradually.
  • A case of misuse has been reported in a patient treated for extensive erythrodermic psoriasis with 240 g of Daivobet ointment per week (corresponding to a daily dose of approximately 34 g) for 5 months (maximum recommended dose 15 g per day); during treatment, the patient developed Cushing’s syndrome followed by pustular psoriasis after abrupt cessation of treatment.

What should I do if I miss a dose?

Do not apply a double dose to make up for the dose you forgot to apply.

What happens if you stop taking daivobet gel ?

  • Treatment with DAIVOBET should be stopped as instructed by your doctor. It may be necessary to stop treatment gradually, especially if you have been taking it for a long time.
  • If you have any further questions on the use of this medicine, ask your doctor or pharmacist for more information.

What is  Forms and Composition ?

SHAPES and PRESENTATIONS

50 µg / 0.5 mg / g gel (almost transparent, colorless to very slightly off-white):  

  • 60 g vial, unit box.
  • 60 g cartridge, with applicator, unit box.

Ointment at 50 µg / 0.5 mg / g (whitish to yellow):  

  •  Tube of 60 g.

COMPOSITION

  p 1 g of gel
Calcipotriol (INN) monohydrate expressed as calcipotriol 50 µg
Betamethasone (INN) dipropionate expressed as betamethasone 0.5 mg
  • Excipients: liquid paraffin, polyoxypropylene stearyl ether, hydrogenated castor oil, butylhydroxytoluene (E321), all-rac-alpha-tocopherol.
  • Excipients with known effect: 1 g of gel contains 160 µg of butylhydroxytoluene and 20 mg of castor oil.

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
]]>
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xamiol gel Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1759/xamiol.html https://edrug-online.com/1759/xamiol.html#respond Tue, 17 Nov 2020 10:27:36 +0000 https://edrug-online.com/?p=1759 xamiol gel usesGeneric drug of the Therapeutic class: Dermatology Active ingredients: Calcipotriol , Betamethasone what is xamiol medication used for and indication?  Xamiol is used as the topical treatment for scalp psoriasis in adults. Psoriasis is caused by your skin cells being produced too quickly. This causes redness, peeling and thickening of the skin. Xamiol contains calcipotriol and betamethasone. Calcipotriol helps restore the rate […]]]> xamiol gel uses

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Calcipotriol , Betamethasone

what is xamiol medication used for and indication? 

Xamiol is used as the topical treatment for scalp psoriasis in adults. Psoriasis is caused by your skin cells being produced too quickly. This causes redness, peeling and thickening of the skin.

Xamiol contains calcipotriol and betamethasoneCalcipotriol helps restore the rate of growth of skin cells to normal, and betamethasone works by reducing inflammation.

PRESENTATION (S) AVAILABLE FOR XAMIOL 50 ΜG / 0.5 MG / G

4 presentations are available for this drug:

  • 1 bottle (s) high density polyethylene (HDPE) of 15 g
  • 1 bottle (s) high density polyethylene (HDPE) of 30 g
  • 1 bottle (s) high density polyethylene (HDPE) of 60 g
  • 2 high density polyethylene (HDPE) bottle (s) of 60 g
FEATURE DESCRIPTION
Pharmaceutical class psoriasis treatment
Active substance (s) betamethasone dipropionate, calcipotriol monohydrate
General medicine no
Pharmaceutical form gel
Route (s) of administration cutaneous
Social security reimbursement rate 65%
Laboratory (s) LEO
Conditions of issue available by simple prescription

xamiol Dosage

Always take the dose recommended by your doctor. If in doubt, consult your doctor or pharmacist.

How to apply Xamiol:

  • Cutaneous use. Medicinal product only for the scalp.

xamiol Contraindications

  • Hypersensitivity to the active substances or to any of the excipients.
  • Xamiol gel is contraindicated in cases of erythrodermic, exfoliating and pustular psoriasis.
  • Due to the presence of calcipotriol, Xamiol gel is contraindicated in patients with a history of calcium metabolism disorders.
  • Due to the presence of corticosteroids, Xamiol gel is contraindicated in the following cases: skin infections of viral origin (for example herpes or chickenpox), fungal or bacterial, parasitic infections, skin damage related to tuberculosis or syphilis, perioral dermatitis, skin atrophy, stretch marks, fragility of the skin venous network, ichthyosis, acne vulgaris, acne rosacea, rosacea, ulcers, wounds, peri-anal and genital pruritus.

xamiol gel how to use?

Instruction for correct use

  • Only use it for your scalp psoriasis and do not use it on healthy skin.
  • Washing your hair before applying Xamiol is not necessary
  • Shake the bottle before use and remove the cap.
  • Before applying Xamiol to the scalp, style your hair to eliminate dandruff. Tilt your head to make sure that Xamiol is not running on your face. Streaking can make Xamiol easier to apply. Apply Xamiol to the affected area with your fingertip and rub it in gently.
  • Usually, an amount between 1 and 4 g per day is sufficient to treat the scalp (4 g corresponds to a teaspoon).
  • Do not cover the treated area with neither a bandage nor a compression bandage.
  • Wash hands thoroughly after using Xamiol. This will prevent accidental transfer of gel to other parts of the body (especially on the face, mouth and eyes).
  • Don’t worry if you accidentally apply the gel to healthy skin around the psoriasis lesions, but wipe it off if it gets too wide.
  • For optimal effect, it is recommended not to wash your hair immediately after applying Xamiol. Leave Xamiol in contact with the scalp overnight or during the day.
  • After applying the gel, avoid contact with fabrics that are easily stained with grease (such as silk).

    How do I use Xamiol gel
    How do I use Xamiol gel

Washing your hair before applying Xamiol is not necessary.

  1. Shake the bottle before use.
  2. Apply a drop of Xamiol to the fingertip.
  3. Apply directly to the affected areas where you can feel the plaque and massage Xamiol gel into the skin. Depending on the affected area 1-4 g (the equivalent of a teaspoon) is normally sufficient.

For optimal effect, it is recommended not to wash your hair immediately after applying Xamiol. Leave X amiol in contact with the scalp overnight or during the day. When washing your hair after application, follow these recommendations:

  1. Apply a mild shampoo to dry hair, especially where the gel has been applied.
  2. Leave the shampoo on the scalp for a few minutes before washing off.
  3. Wash your hair normally.

It may be necessary to repeat steps 4 to 6 once or twice.

Duration of the treatment

  • Use the gel once a day. It may be more convenient to apply the gel in the evening
  • The normal initial treatment period is 4 weeks
  • Your doctor may prescribe a different duration of treatment.
  • Your doctor may decide to repeat the treatment.
  • Do not use more than 15 grams per day

All affected areas can be treated with Xamiol. However, if you are using other products containing calcipotriol, the total calcipotriol should not exceed 15 grams per day and the treated area should not exceed 30% of the total body surface area.

What should I expect from my treatment with X amiol?

Most patients see a clear result after 2 weeks even if the psoriasis has not completely gone away.

how does xamiol work?

Pharmacotherapeutic group: Anti-psoriatic drugs. Other anti-psoriatic drugs for topical use, Calcipotriol, combinations, ATC code: D05AX52.

  • Calcipotriol is an analogue of vitamin D. In vitro data suggest that calcipotriol induces differentiation and inhibits the proliferation of keratinocytes. This is the mechanism proposed to explain its effects in psoriasis.
  • Like other topical corticosteroids, betamethasone dipropionate has anti-inflammatory, anti-pruritic, vasoconstrictive, and immunosuppressive properties, however, with no demonstrated curative action. Treatment under occlusion may increase the effect due to greater penetration into the stratum corneum. The incidence of side effects will therefore be increased. In general, the mechanism of action of the anti-inflammatory activity of topical corticosteroids is not fully understood.
  • The adrenal response to ACTH was determined by measuring cortisol in patients with both extensive scalp and body psoriasis using up to 106 g per week of Xamiol gel in combination with Daivobet ointment. A borderline decrease in cortisol levels 30 minutes after ACTH administration was observed in 5 of 32 patients (15.6%) after 4 weeks of treatment and in 2 of 11 patients (18.2%) who had prolonged treatment up to 8 weeks. In all cases, cortisol levels were at a normal level 60 minutes after the administration of ACTH. No changes in calcium metabolism were observed in these patients. Regarding hypothalamic-pituitary braking, this study demonstrates that
  • The efficacy of once-daily use of Xamiol gel has been evaluated in two randomized, double-blind, 8-week clinical studies including a total of over 2,900 patients with scalp psoriasis of severe severity. less mild according to the Investigator’s Global Assessment of disease severity (IGA). The comparators were betamethasone dipropionate in the gel vehicle, calcipotriol in the gel vehicle, and (in one of the studies) the gel vehicle alone, all used once daily. Results for the primary endpoint (absence of disease or very slight presence of disease according to IGA at week 8) showed that Xamiol gel was significantly more effective than the comparators. The results on the speed of
% of patients with absence of disease or very slight presence of disease Xamiol gel (n = 1,108) Betamethasone dipropionate (n = 1118) Calcipotriol

(n = 558)

Freeze vehicle (n = 136)
week 2 53.2% 42.8% 1 17.2% 1 11.8% 1
week 8 69.8% 62.5% 1 40.1% 1 22.8% 1

1 Statistically less effective than Xamiol gel (p <0.001)

  • Another randomized, single-blind, clinical study including 312 patients with scalp psoriasis of at least moderate severity according to the IGA investigated the use of Xamiol gel once daily compared with that of Daivonex scalp solution two. times a day for 8 weeks. Results for the primary endpoint (absence of disease or very mild disease presence according to the IGA at week 8) showed that Xamiol gel was statistically more effective than Daivonex scalp solution.
% of patients with absence of disease or very slight presence of disease Xamiol gel (n = 207) Daivonex Scalp Solution (n = 105)
week 8 68.6% 31.4% 1

1 Statistically less effective than Xamiol gel (p <0.001)

  • A long-term, randomized, double-blind clinical study including 873 patients with scalp psoriasis of at least moderate severity at baseline (according to the IGA) studied the use of Xamiol gel in comparison with that of calcipotriol in the vehicle of the gel. Both treatments were applied once daily, intermittently as needed, for up to 52 weeks. Adverse effects possibly linked to the long-term use of corticosteroids on the scalp have been identified blindly by an independent panel of dermatologists. There was no difference in the percentage of patients with such adverse effects between the treated groups (2.6% in the Xamiol gel group and 3.0% in the calcipotriol group; p = 0.73). No case of skin atrophy

Pediatric population

  • The effects on calcium metabolism were studied in two open-label, 8-week, open-label studies including a total of 109 adolescents aged 12 to 17 years with scalp psoriasis who used up to 69 g per week of Xamiol gel. No cases of hypercalcaemia and no clinically relevant changes in calciuria have been reported. The adrenal response to the administration of ACTH was measured in 30 patients; one patient showed a slight decrease in his cortisol levels on administration of ACTH after 4 weeks of treatment, without clinical manifestation and reversible

How To Store xamiol ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the vial after EXP. The expiration date refers to the last day of that month.
  • Do not put in the refigerator. Store in the outer packaging in order to protect from light.
  • The bottle should be discarded 6 months after first opening with the gel it contains.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

xamiol Side Effects

Like all medicines, Xamiol can cause side effects, although not everybody gets them.

About 1 in 12 people may experience side effects, but most are reactions at the site of application of the gel.

Serious side effects

Contact your doctor / nurse immediately or as soon as possible if any of these reactions occur. You may need to stop your treatment

The following serious side effects have been reported for Xamiol

Uncommon (affects less than 1 in 100 people)

  • Worsening of your psoriasis. If your psoriasis gets worse, talk to your doctor as soon as possible.

Serious side effects are known to be caused by betamethasone (a strong corticosteroid), one of the ingredients of Xamiol. Tell your doctor as soon as possible if a serious side effect occurs. These side effects most often occur after prolonged use, or under occlusion. These effects include the following:

  • Your adrenal glands may stop working properly. The signs are fatigue, depression, and worry.
  • Cataracts (signs are blurry and blurred vision, difficulty seeing at night, and sensitivity to light) or increased pressure in the eye (signs are eye pain, red eye, decreased or cloudy vision).
  • Infections (because your infection-fighting immune system may be weakened or weakened).
  • Pustular psoriasis (a red area with yellowish pustules usually on the hands or feet). If you notice it, stop using Xamiol and talk to your doctor as soon as possible.
  • Impact on the control of the metabolism of diabetes mellitus (if you are diabetic you may have fluctuations in your blood sugar).

Serious side effects are known to be caused by calcipotriol:

  • Allergic reactions with severe swelling of the face or other parts of the body such as the hands or feet. Swelling of the lips / throat and difficulty in breathing may occur. If you have an allergic reaction, stop using Xamiol, tell your doctor straight away, or go to the nearest hospital emergency room.
  • Treatment with this gel may increase your calcium levels in the blood or urine (usually when too much gel has been used). Signs of increased calcium in the blood are bone pain, constipation, loss of appetite, nausea, and vomiting. This can be serious and you should contact your doctor immediately. However, when treatment is stopped, the levels return to normal.

Less serious side effects

The following less serious side effects have been reported with Xamiol

Common side effects (affect less than 1 in 10 people)

  • Itching.

Uncommon side effects (affect less than 1 in 100 people)

  • Eye irritation.
  • Burning sensation of the skin.
  • Skin pain or irritation.
  • Inflammation or swelling of the hair roots (folliculitis).
  • Redness with inflammation of the skin (dermatitis).
  • Redness of the skin due to the dilation of small blood vessels (erythema).
  • Acne (pimples).
  • Dry skin.
  • Eruptions.
  • Rash of pustules.

Less serious side effects caused by betamethasone when used for a long time include the following side effects, and you should tell your doctor or nurse as soon as possible if you notice them:

  • Thinning of the skin.
  • Appearance of surface veins or stretch marks.
  • Change in hair growth.
  • Redness around the mouth (perioral dermatitis).
  • Red rash with inflammation and swelling (allergic contact dermatitis).
  • Small white buttons (colloid milium).
  • Depigmentation (lightening of the skin).

Less serious side effects are known to be caused by calcipotriol, including the following:

  • Sensitivity of the skin to light causing a rash.
  • Eczema.

If you notice the effects described above or other changes during treatment, tell your doctor.

If you experience any of the side effects listed as serious, or if you experience any side effects not listed in this leaflet, please tell your doctor or pharmacist.

Keep out of the reach and sight of children.

xamiol Interactions

  • No interaction studies have been performed with Xamiol.
  • In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.

Effects on ability to Drive and use machines

  • Xamiol gel has no or negligible influence on the ability to drive and use machines.

Warnings and Precautions

Take special care with Xamiol:

Before using this medication, tell your doctor or pharmacist if:

  • you are taking other medicines which contain corticosteroids as you may have side effects
  • you have taken this medicine for a long time and plan to stop the treatment (as there is a risk that your psoriasis will get worse or come back when the corticosteroids are suddenly stopped),
  • you have diabetes (diabetes mellitus) because blood sugar / glucose levels may be affected by corticosteroids
  • your skin becomes infected because you may need to stop treatment,
  • you have psoriasis of a type called gouty psoriasis
  • you have severe liver or kidney disease.

Special precautions

  • Avoid treating more than 30% of the body and using more than 15 grams per day.
  • Avoid use under a shower cap, bandages or dressings as this increases the absorption of corticosteroids.
  • Avoid use on large areas of damaged skin or in skin folds (groin, under the arms, under the breasts) as this increases the systemic absorption of corticosteroids.
  • Avoid use on the face or the genitals (sexual organs) as these are very sensitive to corticosteroids.
  • Avoid excessive exposure to the sun, excessive use of solar cabins, or other form of light therapy.

Children

  • Xamiol is not recommended for children under the age of 18.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • There are insufficient data from the use of Xamiol gel in pregnant women. Studies in animals with glucocorticoids have shown reproductive toxicity (see section Preclinical safety data), but a number of epidemiological studies (less than 300 completed pregnancies) have not shown congenital abnormalities in infants born to mothers treated with corticosteroids during pregnancy. The potential risk to humans is uncertain. Therefore, Xamiol gel should only be used during pregnancy when the potential benefit justifies the potential risk.

Feeding with milk

  • Betamethasone passes into breast milk, but the risk of an adverse effect in the infant seems unlikely at therapeutic doses. There are no data available on the excretion of calcipotriol in human milk. Caution should be exercised when prescribing Xamiol gel to breast-feeding women.

Fertility

  • Studies in rats following oral administration of calcipotriol or betamethasone dipropionate have shown no impairment of fertility in males and females (see section Preclinical safety data).

What happens if I overdose from xamiol ?

  • The use of doses higher than the recommended dose may lead to an increase in serum calcium, this effect is reversible on discontinuation of treatment. Symptoms of hypercalcemia include polyuria, constipation, muscle weakness, confusion, and coma.
  • Excessive and prolonged use of topical corticosteroids can lead to hypothalamic-pituitary axis slowing, resulting in secondary adrenal insufficiency which is usually reversible. In this case, symptomatic treatment is indicated.
  • In the event of chronic toxicity, treatment with corticosteroids should be withdrawn gradually.
  • A case of misuse has been reported in a patient treated for extensive erythrodermic psoriasis with 240 g of Daivobet ointment per week (corresponding to a daily dose of approximately 34 g) for 5 months (maximum recommended dose 15 g per day); during treatment, the patient developed Cushing’s syndrome followed by pustular psoriasis after abrupt cessation of treatment.

What should I do if I miss a dose?

Do not apply a double dose to make up for the dose you forgot to apply.

What happens if you stop taking xamiol ?

Treatment with XAMIOL should be stopped as instructed by your doctor. It may be necessary to stop treatment gradually, especially if you have been taking it for a long time.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist for more information.

What is  Forms and Composition ?

SHAPES and PRESENTATIONS

50 µg / 0.5 mg / g gel (almost transparent; colorless to very slightly off-white): 60 g vial.

COMPOSITION

p gram
Calcipotriol monohydrate expressed as calcipotriol 50 µg
Betamethasone dipropionate expressed as betamethasone 0.5 mg

Excipients: liquid paraffin, polyoxypropylene stearyl ether, hydrogenated castor oil, butylhydroxytoluene (E321), all-rac-alpha-tocopherol.

Excipients with known effect: butylhydroxytoluene (E321) (160 micrograms / g), castor oil (20 mg / g).

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
]]>
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Daivobet ointment Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/1743/daivobet-ointment.html https://edrug-online.com/1743/daivobet-ointment.html#respond Tue, 17 Nov 2020 10:27:32 +0000 https://edrug-online.com/?p=1743 daivobet ointment usesGeneric drug of the Therapeutic class: Dermatology Active ingredients: Calcipotriol , Betamethasone what is daivobet ointment medication used for and indication? Daivobet ointment is used on the skin to treat plaque psoriasis (psoriasis vulgaris) in adults. Psoriasis is caused by your skin cells being produced too quickly. This results in redness, peeling and thickening of the skin. Daivobet contains calcipotriol and […]]]> daivobet ointment uses

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Calcipotriol , Betamethasone

what is daivobet ointment medication used for and indication?

Daivobet ointment is used on the skin to treat plaque psoriasis (psoriasis vulgaris) in adults. Psoriasis is caused by your skin cells being produced too quickly. This results in redness, peeling and thickening of the skin.

Daivobet contains calcipotriol and betamethasoneCalcipotriol helps restore the rate of growth of skin cells to normal, and betamethasone works by reducing inflammation.

PRESENTATION (S) AVAILABLE FOR DAIVOBET 50 ΜG / 0.5 MG / G

3 presentations are available for this drug:

  • 1 tube (s) painted aluminum of 15 g
  • 1 painted aluminum tube (s) of 30 g
  • 1 60 g painted aluminum tube (s)
FEATURE DESCRIPTION
Pharmaceutical class psoriasis treatment
Active substance (s) per 1 g: betamethasone dipropionate (0.643 mg), calcipotriol monohydrate (52.2 micrograms)
General medicine no
Pharmaceutical form ointment
Route (s) of administration cutaneous
Social security reimbursement rate 65%
Laboratory (s) LEO
Conditions of issue available by simple prescription

daivobet ointment Dosage

Dosage

  • Daivobet ointment should be applied once a day to the lesions. The recommended duration of treatment is 4 weeks. There are data on the use of repeated courses of Daivobet for up to 52 weeks. If it is necessary to continue or resume treatment after 4 weeks, treatment should be continued after medical advice and under regular medical supervision.
  • When using products containing calcipotriol, the maximum daily dose should not exceed 15 g. The body surface area treated with products containing calcipotriol should not exceed 30% (see section Warnings and precautions for use ).

Special populations

Renal and hepatic failure

  • The safety and efficacy of Daivobet ointment in patients with severe renal impairment or severe hepatic impairment have not been evaluated.

Pediatric population

  • The safety and effectiveness of Daivobet ointment in children below the age of 18 have not been established. No data is available.

daivobet ointment Contraindications

  • Known hypersensitivity to the active substances or to any of the excipients.
  • Daivobet ointment is contraindicated in erythrodermic, exfoliating and pustular psoriasis.
  • Due to the presence of calcipotriol, Daivobet ointment is contraindicated in patients with a history of calcium metabolism disorders.
  • Due to the presence of corticosteroids, Daivobet ointment is contraindicated in the following cases: skin lesions of viral origin (for example herpes or chickenpox), infections of fungal or bacterial origin, parasitic infections, related skin damage with tuberculosis or syphilis, perioral dermatitis, skin atrophy, stretch marks, fragility of the cutaneous venous network, ichthyosis, acne vulgaris, acne rosacea, rosacea, ulcers, wounds, peri-anal and genital itching.

How To Take daivobet ointment ?

How to apply Daivobet

  • Cutaneous use.

Instruction for correct use

  • Apply the product only to psoriasis and not to skin that does not have psoriasis.
  • Remove the cap and check that the tube is tightly closed before using the ointment for the first time.
  • To pierce the seal, use the point on the back of the cap.
  • Squeeze the ointment out on a clean finger.
  • Rub gently to work into the skin, covering the area with psoriasis, until most of the ointment is gone in the skin.
  • Do not cover the treated area with neither a bandage nor a tight bandage.
  • Wash your hands thoroughly after using Daivobet (unless you are using the ointment to treat your hands. This will prevent accidental transfer of the ointment to other parts of the body (especially to the face, scalp, mouth and eyes). ).
  • Don’t worry if you accidentally apply the ointment to healthy skin around the psoriasis lesions, but wipe it off if it gets too much.
  • For optimal effect, it is recommended not to shower or bathe immediately after applying Daivobet ointment.
  • After applying the ointment, avoid contact with fabrics that are easily stained with grease (such as silk).

Duration of the treatment

  • Use the ointment once a day. It may be more convenient to apply the ointment in the evening.
  • The initial treatment period is normally 4 weeks, but your doctor may prescribe a different duration of treatment.
  • Your doctor may decide to repeat the treatment.
  • Do not use more than 15 grams per day.

If you are using other products containing calcipotriol, the total calcipotriol should not exceed 15 grams per day and the treated area should not exceed 30% of the total body surface.

What should I expect from my treatment with Daivobet?

Most patients see a clear result after 2 weeks even if the psoriasis has not completely gone away.

how does daivobet ointment work?

Pharmacotherapeutic group: Antipsoriatics. Other anti-psoriatic drugs for topical use, Calcipotriol, combinations, ATC code: D05AX52.

  • Calcipotriol is an analogue of vitamin D. In vitro data suggest that calcipotriol induces differentiation and inhibits the proliferation of keratinocytes. This is the mechanism proposed to explain its effects in psoriasis.
  • Like other topical corticosteroids, betamethasone dipropionate has anti-inflammatory, anti-pruritic, vasoconstrictive, and immunosuppressive properties, with no demonstrated curative action. Treatment under occlusion may increase the effect due to greater penetration into the stratum corneum. The incidence of side effects will therefore be increased. The mechanism of action of the anti-inflammatory activity of topical corticosteroids is not fully established.
  • A safety study in 634 psoriatic patients investigated the effects of repeated courses of Daivobet ointment used once daily as needed, either alone or alternately with Daivonex, for up to 52 weeks compared with Daivonex used alone for 48 weeks afterwards. initial treatment with Daivobet ointment. Adverse effects were reported by 21.7% of patients in the Daivobet ointment group, 29.6% in the Daivobet ointment / Daivonex alternating group and 37.9% in the Daivonex group. The side effects reported by more than 2% of patients in the Daivobet ointment group are pruritus (5.8%) and psoriasis (5.3%). Side effects which may be related to long-term treatment with corticosteroids (e.g. skin atrophy, folliculitis, depigmentation,
  • The adrenal response to ACTH was determined by measuring cortisol in patients with both extensive scalp and body psoriasis using up to 106 g per week of Daivobet gel in combination with Daivobet ointment. A borderline decrease in cortisol levels 30 minutes after ACTH administration was observed in 5 of 32 patients (15.6%) after 4 weeks of treatment and in 2 of 11 patients (18.2%) who had prolonged treatment up to 8 weeks. In all cases, cortisol levels were at a normal level 60 minutes after the administration of ACTH. No changes in calcium metabolism were observed in these patients. Regarding hypothalamic-pituitary braking, this study demonstrates that

Pediatric population

  • The adrenal response to ACTH administration was measured in an uncontrolled 4-week study in 33 adolescents aged 12 to 17 years with psoriasis of the body who used up to 56 g per week of Daivobet ointment. . No case of hypothalamic-pituitary axis braking has been reported. No hypercalcaemia was reported, but one patient had an increase in urinary calcium possibly related to treatment.

How To Store daivobet ointment ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the tube or carton after EXP. The expiration date refers to the last day of that month.
  • Store the product at a temperature not exceeding 25 ° C.
  • The tube should be discarded 1 year after first use.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

daivobet ointment Side Effects

Like all medicines, Daivobet can cause side effects, although not everybody gets them.

About 1 in 10 people may experience side effects, but most are reactions at the site of the ointment application and are usually mild and temporary.

Serious side effects:

The following serious side effects have been reported for Daivobet:

Uncommon (affects less than 1 in 100 people)

  • Worsening of your psoriasis. If your psoriasis gets worse, talk to your doctor as soon as possible.

Rare (affect less than 1 in 1,000 people)

  • Pustular psoriasis may occur (a red area with yellowish pustules usually on the hands or feet). If you notice these symptoms, stop using Daivobet and tell your doctor as soon as possible.

Serious side effects are known to be caused by betamethasone (a strong corticosteroid), one of the ingredients of Daivobet. Tell your doctor as soon as possible if a serious side effect occurs:

  • Your adrenal glands may stop working properly. The symptoms are fatigue, depression and anxiety.
  • Cataract (signs are blurry or blurred vision, difficulty seeing at night, and sensitivity to light) or increased pressure in the eye (signs are eye pain, red eye, decreased vision or blurred vision).
  • Infections (because your infection-fighting immune system may be weakened or weakened)
  • Impact on the control of the metabolism of diabetes mellitus (if you are diabetic you may have fluctuations in your blood sugar).

These side effects most often occur after prolonged use, use in the folds (eg groin, under the arms or under the breasts), use under bandages and dressings or on large areas of skin.

Serious side effects are known to be caused by calcipotriol:

  • Allergic reactions with severe swelling of the face or other parts of the body such as the hands or feet. Swelling of the mouth and / or throat and difficulty in breathing may occur. If you have an allergic reaction, stop using Daivobet, tell your doctor straight away, or go to the nearest hospital emergency room.
  • Treatment with this ointment may increase your calcium levels in the blood or urine (usually when too much ointment has been used). Signs of increased calcium in the blood are bone pain, constipation, loss of appetite, nausea, vomiting. This can be serious and you should contact your doctor as soon as possible. However, when treatment is stopped, the levels return to normal.

Less serious side effects:

The following less serious side effects have also been reported with Daivobet.

If any of these effects last a long time or bothers you, tell your doctor or nurse.

Common side effects (affect less than 1 in 10 people):

  • Itching.
  • Rashes.
  • Burning sensation.

Uncommon side effects (affect less than 1 in 100 people):

  • Skin pain or irritation.
  • Rash with inflammation of the skin (dermatitis).
  • Redness of the skin due to the dilation of small blood vessels (erythema).
  • Inflammation or swelling of the hair roots (folliculitis).
  • Change in skin color on the areas where you applied the ointment.

Unknown frequency

  • Rebound effect: worsening of your symptoms / psoriasis after stopping treatment

Less serious side effects caused by betamethasone include the following. You should tell your doctor as soon as possible if you notice them:

  • Thinning of the skin.
  • Appearance of surface veins or stretch marks.
  • Change in hair growth.
  • Redness around the mouth (perioral dermatitis).
  • Red rash with inflammation and swelling (allergic contact dermatitis).
  • Shiny brown botons filled with gel (colloid millium).
  • Lightening of the skin (depigmentation).

Less serious side effects caused by calcipotriol include the following:

  • Dry skin.
  • Sensitivity of the skin to light resulting in a rash has also been reported.
  • Eczema.

If you notice the side effects described above or other changes during treatment, tell your doctor.

If you experience any of the side effects listed as serious, or if you experience any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

Keep out of the reach and sight of children.

daivobet ointment Interactions

  • No interaction studies have been performed with Daivobet.

In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.

Effects on ability to Drive and use machines

This medicine is not expected to have any effect on your ability to drive or use machines.

Warnings and Precautions

Take special care with Daivobet

Before using other medicines, ask your doctor / nurse / pharmacist if:

  • you are taking other medicines that contain corticosteroids as you may have side effects
  • you have been taking this medicine for a long time and plan to stop the treatment as there is a risk that your psoriasis will get worse or “flare up” when corticosteroids are suddenly stopped)
  • you have diabetes (diabetes mellitus) because blood sugar / glucose levels may be affected by corticosteroids.
  • your skin becomes infected because you may need to stop treatment
  • you have psoriasis of a type called gouty psoriasis
  • you have severe liver or kidney disease.

Special precautions

  • Avoid treating more than 30% of the body and using more than 15 grams per day.
  • Avoid use under bandages or dressings as this increases the absorption of corticosteroids.
  • Avoid use on large areas of injured skin or in skin folds (groin, under the arms, under the breasts) as this increases the absorption of corticosteroids.
  • Avoid use on the face or genitals (sexual organs) as these are very sensitive to corticosteroids.
  • Avoid excessive sun exposure, excessive use of solar cabins or other form of light therapy.

Children

  • Daivobet is not recommended for children under the age of 18.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • There are no relevant data from the use of Daivobet in pregnant women. Animal studies with glucocorticoids have shown reproductive toxicity ( see Preclinical Safety ), but a number of epidemiological studies (less than 300 pregnancies completed) have not shown congenital anomalies in children born to mothers treated with corticosteroids during pregnancy. The potential risk for humans is not known for sure. Therefore, Daivobet should only be used during pregnancy when the potential benefit justifies the potential risk.

Feeding with milk

  • Betamethasone passes into breast milk, but the risk of an adverse effect in the infant seems unlikely at therapeutic doses. There are no data on the excretion of calcipotriol in human milk. Caution should be exercised when prescribing Daivobet in nursing mothers. Do not use Daivobet on the breasts if breastfeeding.

Fertility

  • Studies in rats after oral administration of calcipotriol or betamethasone dipropionate have shown no impairment of fertility in males and females ( see Preclinical Safety ).

What happens if I overdose from daivobet ointment ?

  • The use of doses higher than the recommended dose may lead to an increase in serum calcium, this effect is reversible on discontinuation of treatment. Symptoms of hypercalcemia include polyuria, constipation, muscle weakness, confusion, and coma.
  • Excessive and prolonged use of topical corticosteroids can lead to hypothalamic-pituitary axis slowing, resulting in secondary adrenal insufficiency which is usually reversible. In this case, symptomatic treatment is indicated.
  • In the event of chronic toxicity, treatment with corticosteroids should be withdrawn gradually.
  • A case of misuse has been reported in a patient treated for extensive erythrodermic psoriasis with 240 g of Daivobet ointment per week (corresponding to a daily dose of approximately 34 g) for 5 months (maximum recommended dose 15 g per day); during treatment, the patient developed Cushing’s syndrome followed by pustular psoriasis after abrupt cessation of treatment.

What should I do if I miss a dose?

Do not apply a double dose to make up for the dose you forgot to apply.

What happens if you stop taking daivobet ointment ?

Treatment with DAIVOBET should be stopped as instructed by your doctor. It may be necessary to stop the treatment gradually, especially if you have been using it for a long time.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist for more information.

What is  Forms and Composition ?

SHAPES and PRESENTATIONS

Ointment at 50 µg / 0.5 mg / g (whitish to yellow):  

  •  Tube of 60 g.

50 µg / 0.5 mg / g gel (almost transparent, colorless to very slightly off-white):  

  • 60 g vial, unit box.
  • 60 g cartridge, with applicator, unit box.

COMPOSITION

  p 1 g
Calcipotriol 50 µg
(in monohydrate form: 52.20 µg / g)
Betamethasone 0.50 mg
(as dipropionate: 0.643 mg / g)
  • Excipients: liquid paraffin, polyoxypropylene stearyl ether, all-rac-alpha-tocopherol, white petrolatum, butylhydroxytoluene (E321).
  • Excipient with known effect: 1 g of ointment contains 50 micrograms of butylhydroxytoluene (E321).

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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Baseal 5 mg / ml Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/2030/baseal.html https://edrug-online.com/2030/baseal.html#respond Mon, 16 Nov 2020 13:26:05 +0000 https://edrug-online.com/?p=2030 BASEAL 5 mg / ml, solution for skin application, 125 ml vialGeneric drug of the Therapeutic class: Dermatology Active ingredients: Chlorhexidine Medicinal product withdrawn from the market on 09/14/2010 what is Baseal medication used for and indication? Antisepsis of superficial wounds and of weak extent. Note : Antiseptic agents are not sterilizing: they temporarily reduce the number of microorganisms. Baseal Dosage A spray twice a day, directly on the […]]]> BASEAL 5 mg / ml, solution for skin application, 125 ml vial

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Chlorhexidine

Medicinal product withdrawn from the market on 09/14/2010

what is Baseal medication used for and indication?

Antisepsis of superficial wounds and of weak extent.

Note : Antiseptic agents are not sterilizing: they temporarily reduce the number of microorganisms.

Baseal Dosage

A spray twice a day, directly on the wound.

Baseal Contraindications

  • Hypersensitivity to chlorhexidine or to any of the ingredients.
  • Do not apply in the eyes, ears or on mucous membranes.
  • This product must not penetrate into the auditory canal, in particular in the event of tympanic perforation, nor, in general, be placed in contact with nervous tissue or the meninges.
  • This specialty cannot be used for the disinfection of microsurgical equipment or for the antisepsis of healthy skin before surgery (antisepsis of the operating field and antisepsis of puncture, injection or transfusion areas).

How To Take Baseal ?

Method of administration :

The solution is ready to use. It is to be applied directly to the wounds.

how does Baseal work?

Transcutaneous absorption of chlorhexidine through the skin in a physiological state is negligible, even in newborns.

How To Store Baseal ?

Keep out of the reach and sight of children.

Expiration date

Do not use BASEAL 5 mg / g,  after the expiry date stated on the box.

Storage conditions

There are no special storage precautions.

If necessary, warnings against certain visible signs of deterioration

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist what to do with any unused medicine. These measures will help protect the environment.

Baseal Side Effects

Risk of local allergy, usually manifested by contact eczema.

Risk of general allergy up (rarely) to anaphylactic shock, particularly when used on:

  • the injured skin
  • mucous membranes
  • ulcerations of the lower limbs, with the possibility of aggravation of a superinfected lesion during prolonged use.

Baseal Interactions

Given the possible interferences (antagonism, inactivation), the simultaneous or successive use of antiseptics should be avoided except with the other cationic components.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

WARNINGS

  • External use only.
  • Risk of sensitization to chlorhexidine.
  • Although the transcutaneous absorption of chlorhexidine is very low, the risk of systemic passage cannot be excluded. These systemic effects could be favored by repeated applications, by use on a large skin area, under an occlusive dressing, on injured skin (especially burned), mucous membranes, premature or infant skin (due to the report area / weight and the effect of occlusion of layers at the seat).
  • As soon as the packaging of an antiseptic preparation is opened, microbial contamination is possible.

PRECAUTIONS FOR USE

  • Any antiseptic should be used with precautions in conditions where a systemic effect may be feared, in particular in infants, in the event of damaged skin, or on a large surface (see section warnings).

PREGNANCY & BREAST-FEEDING & FERTILITY

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if I overdose from Baseal ?

  • In the event of massive oral ingestion, perform gastric lavage. The acute oral toxicity of chlorhexidine is low (digestive absorption almost negligible).
  • Contact a poison control center.

What should I do if I miss a dose?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking Baseal ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Lack of information in the MA.
  • 125 ml in a bottle (HDPE) closed with a pump cap (PE and polypropylene).

Composition

Active ingredient Solution for skin application
Chlorhexidine 0.5 g *
* per unit dose

Active ingredients: Chlorhexidine
Excipients: 
  • Decyl polyglucoside aqueous solution .
  • Glycerol.
  • Trolamine qs pH = 5.25-6.25 .
  • Purified water.

No excipient with known effect 

  • is not present in the composition of this drug

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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cyteal foaming solution Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/2042/cyteal.html https://edrug-online.com/2042/cyteal.html#respond Mon, 16 Nov 2020 13:25:59 +0000 https://edrug-online.com/?p=2042 cyteal antiseptic foaming solution 500Generic drug of the Therapeutic class: Dermatology active ingredients: Hexamidine ,Chlorhexidine ,Chlorocresol what is cyteal ? This product is a low activity antiseptic containing hexamidine and chlorhexidine in foaming solution. what is cyteal medication used for and indication? It is indicated in the cleansing of the affections of the skin and mucous membranes, infected or at risk […]]]> cyteal antiseptic foaming solution 500

Generic drug of the Therapeutic class: Dermatology
active ingredients: Hexamidine ,Chlorhexidine ,Chlorocresol

what is cyteal ?

This product is a low activity antiseptic containing hexamidine and chlorhexidine in foaming solution.

what is cyteal medication used for and indication?

It is indicated in the cleansing of the affections of the skin and mucous membranes, infected or at risk of infection.

Presentation (s) available for Cyteal

5 presentations are available for this drug:

  • 1 bottle (s) high density polyethylene (HDPE) of 150 ml
  • 1 bottle (s) high density polyethylene (HDPE) of 200 ml
  • 1 bottle (s) high density polyethylene (HDPE) of 250 ml
  • 1 bottle (s) high density polyethylene (HDPE) of 500 ml
  • 1 bottle (s) high density polyethylene (HDPE) of 1000 ml
FEATURE DESCRIPTION
Pharmaceutical class antiseptics and disinfectants
Active substance (s) per 100 ml of foaming solution: chlorocresol (0.30 g), hexamidine (diisethionate) (0.10 g), chlorhexidine digluconate solution (0.50 ml)
General medicine no
Pharmaceutical form foaming solution
Route (s) of administration cutaneous
Social security reimbursement rate 15%
Laboratory (s) PIERRE FABRE DERMATOLOGY
Conditions of issue restricted prescription drug

cyteal Dosage

  • Always take the dose recommended by your doctor. If in doubt, consult your doctor or pharmacist.
  • This product is used as a liquid soap: pure, or diluted to 1/10, followed by abundant rinsing.
  • Do not store the diluted solution.

cyteal Contraindications

Never use CYTEAL, foaming solution in the following cases:

  • If you are allergic (hypersensitive) to the active substances or to any of the other ingredients of CYTEAL.
  • In the ear canal in case of eardrum perforation or in the eyes,
  • For antisepsis before sampling or surgery,
  • For the disinfection of medico-surgical equipment.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST

How To Take cyteal ?

Method and route of administration

  • SKIN VOTING. DO NOT INJECT. DO NOT SWALLOW.

how does cyteal work?

Pharmacotherapeutic group: ANTISEPTIC AND DISINFECTANTS – Biguanides and amidines, ATC code: D08AC.

(D: Dermatology)

Concentrate solution for skin or mucous membrane application, containing:

  • Chlorhexidine antiseptic cationic biguanide family,
  • Hexamidine, antiseptic cationic diamidines of the group,
  • Chlorocresol from the halogenophenol family.

Low activity antiseptic, bacteriostatic non-bactericidal, trichomonacid, partially inhibited by organic matter.

Formation of complexes with: cork, rubber and other polymers, macromolecules, anionic surfactants (soaps) and nonionics.

How To Store cyteal ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the bottle. The pre-emption date refers to the last day of the month.
  • Store away from light and at a temperature below 25 ° C.
  • Do not throw away any medicine via wastewater or other household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

cyteal Side Effects

Like all medicines, CYTEAL Foaming Solution can cause side effects, although not everybody gets them.

Possibility of benign local manifestations: tingling, itching, burning sensation, skin dryness, redness, especially in case of repeated use.

Due to the presence of hexamidine, more severe local allergic reactions can sometimes occur. They are slowly regressing.

Due to the presence of chlorhexidine, possibility:

  • allergic eczema on contact with the product, especially as it concerns damaged skin, mucous membranes or ulcers of the lower limbs.
  • rarely, general allergic accident.

If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.

Keep out of the reach and sight of children.

cyteal Interactions

  • The association with other antiseptics should be avoided because their effects may cancel each other out.
  • Do not use at the same time as ordinary soap and do not use a cork stopper.
  • If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

CYTEAL has no or negligible influence on the ability to drive and use machines.

Warnings and Precautions

Special warnings

  • Do not use this medication on a large area of ​​skin, on damaged skin (especially burnt), premature or infant skin, without medical advice, because of the risk of passage into the general circulation.
  • As soon as the packaging of an antiseptic preparation is opened, microbial contamination is possible.

Precautions for use

  • Follow with the use of this product with a thorough and abundant rinse.
  • If the vial is greater than 250 ml: The volume of this vial greater than 250 ml exposes a risk of contamination of the solution in the event of prolonged use after opening.
  • IN CASE OF DOUBT, DO NOT HESITATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • There are no or few data from the use of CYTEAL in pregnant women.
  • Animal studies with Chlorhexidine do not reveal any direct or indirect harmful effects on the use of CYTEAL during pregnancy (see section Preclinical safety data).
  • However there are no data on Hexamidine and Chlorocresol.
  • As a precaution, it is best to avoid the use of CYTEAL during pregnancy.

Feeding with milk

  • Excretion of CYTEAL and its metabolites is not known in human milk.
  • A risk to newborns / infants cannot be excluded.
  • Cyteal should not be used during breast-feeding.

Fertility

  • Chlorhexidine has no effect on fertility.
  • There are no data available on the effect of Hexamidine and Chlorocresol on fertility.

What happens if I overdose from cyteal ?

Symptoms

  • No case of overdose has been reported.

Management

  • In the event of accidental ingestion, do not perform gastric lavage (foaming product).
  • General supportive measures should be instituted as deemed necessary by the physician.

What should I do if I miss a dose?

If you forget to use CYTEAL, foaming solution

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking cyteal ?

If you stop using CYTEAL, foaming solution

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

SHAPES and PRESENTATIONS

  • Foaming solution.
  • Pale yellow viscous solution. Foam when shaken.
  • 150 ml, 200 ml, 250 ml, 500 ml or 1000 ml opacified high density polyethylene bottle, closed with an opacified low density polyethylene screw cap.
  • Not all presentations may be marketed.

Other shapes

  • CYTEAL, foaming solution, 250 ml bottle
  • CYTEAL, solid soap, box of 100 g
  • CYTEAL, foaming solution, 1000 ml vial

WHAT IS CYTEAL, FOAMING SOLUTION AND CONTENTS OF THE OUTER PACKAGING

  • This medication is in the form of a foaming solution, in a 150 ml, 200 ml, 250 ml, 500 ml or 1000 ml bottle.
  • Not all presentations may be marketed.

COMPOSITION

  p 100 ml
Hexamidine diisetionate 0.10 g
Chlorhexidine digluconate * 0.5 ml
Chlorocresol 0.30 g
  • Excipients: cocamidopropyl betaine, coconut fatty acid diethanolamide, edetic acid, coniferol fragrance (galbanum resinoid, elemi resinoid, essential oil of Pimenta racemose, isobornyl acetate, decanal-2-methylundecanal), lactic acid, purified water .
  • *  20% m / v solution.

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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Hibidil solution for local application Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/2058/hibidil.html https://edrug-online.com/2058/hibidil.html#respond Fri, 13 Nov 2020 21:16:54 +0000 https://edrug-online.com/?p=2058 HIBIDIL, solution for local application, sterile, box of 25 single-dose containers of 15 mlGeneric drug of the Therapeutic class: Dermatology active ingredients: Chlorhexidine what is Hibidil medication used for and indication? Local adjunctive treatment of primarily bacterial skin conditions or likely to become superinfected. NB: antiseptic agents are not sterilizing: they temporarily reduce the number of microorganisms. Presentation (s) available for Hibidil 5 presentations are available for this drug: […]]]> HIBIDIL, solution for local application, sterile, box of 25 single-dose containers of 15 ml

Generic drug of the Therapeutic class: Dermatology

active ingredients: Chlorhexidine

what is Hibidil medication used for and indication?

Local adjunctive treatment of primarily bacterial skin conditions or likely to become superinfected.

NB: antiseptic agents are not sterilizing: they temporarily reduce the number of microorganisms.

Presentation (s) available for Hibidil

5 presentations are available for this drug:

  • 1 polyethylene single-dose container (s) of 15 ml
  • 5 single-dose container (s) of 15 ml
  • 10 single-dose container (s) of 15 ml
  • 25 single-dose container (s) of 15 ml
  • 240 polyethylene single-dose container (s) of 15 ml
FEATURE DESCRIPTION
Pharmaceutical class antiseptics and disinfectants
Active substance (s) per 100 ml: chlorhexidine (digluconate) (50 mg)
General medicine no
Pharmaceutical form solution for sterile application
Route (s) of administration cutaneous
Selling price unregulated price
Social security reimbursement rate 0%
Laboratory (s) Laboratory (s) manufacturer Hibidil
Conditions of issue available without prescription

Hibidil Dosage

  • Ready-to-use, single-use solution.
  • DO NOT SWALLOW. EXTERNAL USE. DERMAL.
  • This product can be applied directly to wounds.
  • Do not rinse.

Hibidil Contraindications

Never use HIBIDIL, solution for local application, sterile in the following cases:

  • Hypersensitivity to one of the components (or group sensitization),
  • In contact with the brain, the meninges, the eye, the mucous membranes, nor penetrate the ear canal in the event of eardrum perforation.

This product must not be used for the disinfection of medico-surgical equipment.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST

How To Take Hibidil ?

Method and route of administration

  • Dermal.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist for more information.

how does Hibidil work?

Pharmacotherapeutic group: antiseptics and disinfectants, ATC code: D08AC02.

How To Store Hibidil ?

  • Keep this medication out of the sight and reach of children.
  • Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date refers to the last day of that month.
  • This medication should be stored at a temperature below 30 ° C.
  • Do not throw away any medicines via a wastewater treatment plant or with household waste. Ask your pharmacist how to throw away the medicines you no longer use. These measures will help protect the environment.

Hibidil Side Effects

Like all medicines, HIBIDIL, solution for topical application, sterile can cause side effects, although not everybody gets them. such as :

  • allergic eczema on contact with the product,
  • rarely, general allergic accident up to anaphylactic shock.
  • Due to the presence of 90 percent ethanol (alcohol), frequent applications to the skin can cause irritation and dryness of the skin.
  • If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
  • Keep out of the reach and sight of children.

Hibidil Interactions

  • This medication should not be used at the same time as other local antiseptics (risk of incompatibility or ineffectiveness). Prior use of soap should be followed by thorough rinsing.
  • If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

Warnings

  • Although the transcutaneous absorption of chlorhexidine is very low, the risk of systemic effects cannot be excluded. They are all the more to be feared as the antiseptic is used over a large area, on damaged skin (in particular burnt) a mucous membrane, premature or infant skin (due to the surface / weight ratio and the diaper occlusion effect at the seat).
  • As soon as the packaging of an antiseptic preparation is opened, microbial contamination is possible.
  • The use of chlorhexidine solutions, alcoholic or aqueous, for antisepsis of the skin, before invasive surgery has been associated with chemical burns in newborns. Based on reported cases and published literature, this risk appears to be higher in premature infants, especially those born before 32 weeks of gestation and in the first 2 weeks of life.
  • Remove all soaked materials, gowns or drape before proceeding. Do not use excessive amounts and do not leave the solution in folds of the skin or on the patient or on sheets or other material in direct contact with the patient. When occlusive dressings are used on areas previously exposed to HIBIDIL, every precaution should be taken to ensure that there is no excess product prior to application of the dressing.

Precautions for use

  • As soon as the packaging of an antiseptic preparation is opened, microbial contamination is possible.
  • Do not use chlorine-based products (bleach, etc.) to clean fabrics or containers that have been in contact with HIBIDIL: risk of indelible stains.

PREGNANCY & BREAST-FEEDING & FERTILITY

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if I overdose from Hibidil ?

In the event of massive oral ingestion, seek the advice of a poison control center.

What should I do if I miss a dose?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking Hibidil ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Solution for local application.
  • 15 ml in single-dose container (polyethylene).

Other shapes

  • HIBIDIL, solution for local application, sterile, box of 240 single-dose containers of 15 ml
  • HIBIDIL, solution for local application, sterile, box of 1 single-dose container of 15 ml

Composition

Active ingredient Sterile solution for local application
Chlorhexidine digluconate 0.5 mg *

* per unit dose

Active ingredients: Chlorhexidine digluconate

Excipients with known effects ?

  • Azorubine
Other excipients: Nonoxinol 9, Ethanol, Gluconolactone (for pH adjustment), Sodium hydroxide (for pH adjustment), Purified water

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

  • Includes a general description of the drug, its use, brand names, FAQs, and relevant news and articles

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
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Alkocortenbioform , cream Uses, Dosage, Side Effects, Precautions & Warnings https://edrug-online.com/2129/alkocortenbioform.html https://edrug-online.com/2129/alkocortenbioform.html#respond Fri, 13 Nov 2020 12:30:29 +0000 https://edrug-online.com/?p=2129 ALKOCORTENBIOFORM, cream, 15 g tubeGeneric drug of the Therapeutic class: Dermatology Active ingredients: Flumetasone , Clioquinol Drug withdrawn from the market on 08/24/2018 what is Alkocortenbioform cream ? This medication is usually prescribed for: Contact eczema Atopic dermatitis Stasis dermatitis Psoriasis Seborrheic dermatitis except the face Insect bite Parasitic prurigo what is Alkocortenbioform cream used for and indication? This medicine contains a corticosteroid of moderate […]]]> ALKOCORTENBIOFORM, cream, 15 g tube

Generic drug of the Therapeutic class: Dermatology
Active ingredients: Flumetasone , Clioquinol

Drug withdrawn from the market on 08/24/2018

what is Alkocortenbioform cream ?

This medication is usually prescribed for:

  • Contact eczema
  • Atopic dermatitis
  • Stasis dermatitis
  • Psoriasis
  • Seborrheic dermatitis except the face
  • Insect bite
  • Parasitic prurigo

what is Alkocortenbioform cream used for and indication?

This medicine contains a corticosteroid of moderate activity and an antiseptic.

It is indicated for certain skin conditions such as contact eczema, atopic dermatitis, but your doctor may prescribe it in other cases.

Presentation (s) available for Alkocortenbioform

1 tube (s) painted aluminum of 15 g

FEATURE DESCRIPTION
Pharmaceutical class not communicated
Active substance (s) per 100 g of cream: clioquinol (3,000 g), flumetasone pivalate (0.020 g)
General medicine no
Pharmaceutical form cream
Route (s) of administration cutaneous
Selling price unregulated price
Social security reimbursement rate 0%
Laboratory (s) Laboratory (s) manufacturer Alkocortenbioform
Conditions of issue available by simple prescription

Alkocortenbioform Dosage

The dosage is 1 to 2 applications per day in a thin layer, followed by a light massage. Do not increase the number of applications per day.

Alkocortenbioform Contraindications

Never use ALKOCORTENBIOFORM, cream in the following cases:

  • allergy to any component of the drug
  • ulcerated lesions
  • acne
  • rosacea
  • infectious diseases of the skin of viral (herpes, shingles, chickenpox, etc.), bacterial (example: impetigo, etc.), mycotic (due to microscopic fungi) or parasitic origin.
  • application on the eyelids

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK FOR THE OPINION OF YOUR DOCTOR OR YOUR PHARMACIST.

How To Take Alkocortenbioform ?

Method and route of administration

DERMAL

  • It is advisable to apply the product in spaced strokes, then to spread it by massaging lightly until it is fully absorbed.
  • Wash hands after application.

Frequency of administration

  • 1 to 2 applications per day as prescribed by your doctor

Duration of treatment

  • The treatment will be stopped gradually, by spacing out the applications and / or by using a less strong or less dosed corticosteroid.
  • Strictly follow your doctor’s prescription and do not prolong the treatment.

how does Alkocortenbioform work?

Association of a moderate activity DERMOCORTICOIDE and an ANTISEPTIC.

(D: dermatology).

  • Topical corticosteroids are classified into 4 activity levels according to skin vasoconstriction tests: very strong, strong, moderate, weak activity.
  • Locacortene Vioforme contains a corticosteroid of moderate activity and an antiseptic, clioquinol.
  • Flumetasone pivalate is the essential active substance.
  • Active on certain inflammatory processes (for example: contact hypersensitivity) and the pruritic effect which is linked to them. Vasoconstrictor. Inhibits cell multiplication.

How To Store Alkocortenbioform ?

  • Keep out of the reach and sight of children.

Expiration date

  • Do not use ALKOCORTENBIOFORM, cream after the expiry date stated on the outer packaging.

Storage conditions

  • Store at a temperature below 25 ° C.

If necessary, warnings against certain visible signs of deterioration

  • Medicines must not be disposed of via wastewater or household waste. Ask your pharmacist what to do with any unused medicine. These measures will help to protect the environment.

Alkocortenbioform drug Side Effects

Like all medicines, ALKOCORTENBIOFORM, cream can cause side effects, although not everybody gets them:

Due to the presence of a corticosteroid

  • With prolonged use, there is a risk of thinning and fragility of the skin, dilation of small blood vessels, stretch marks, acne breakout.
  • Cases of exaggerated development of the hair system, discoloration of the skin, secondary infection in particular in the event of treatment under an occlusive dressing or in the folds, have been reported.

Due to the presence of the antiseptic:

Skin allergy

  • Yellowish discoloration of the skin disappearing quickly.
  • If you notice any side effects not listed in this leaflet, or if any side effects get serious, please tell your doctor or pharmacist.
  • Keep out of the reach and sight of children.

Alkocortenbioform Interactions

If you are taking or have recently taken any other medicines, including medicines obtained without a prescription, talk to your doctor or pharmacist.

Effects on ability to Drive and use machines

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

Warnings and Precautions

WARNINGS

  • The prolonged use on the face of corticosteroids with moderate activity exposes to the occurrence of corticosteroid-induced and paradoxically corticosensitive dermatitis, with rebound after each stop. A gradual weaning, particularly difficult, is then necessary.
  • Due to the passage of the corticosteroid into the systemic circulation, treatment over large areas or under occlusion may cause the systemic effects of systemic corticosteroid therapy, particularly in infants and toddlers. They consist of a cushingoid syndrome and a slowing of growth. These accidents disappear when treatment is stopped, but abrupt cessation can be followed by acute adrenal insufficiency.

PRECAUTIONS FOR USE

  • In infants, it is preferable to avoid corticosteroids of moderate activity. One should be particularly wary of spontaneous occlusion phenomena which may occur in the folds or under the layers.
  • In the event of a bacterial or mycotic infection of a corticosensitive dermatosis, precede the use of the corticosteroid with a specific treatment.
  • If a local intolerance appears, the treatment must be interrupted and the cause must be sought.
  • Breast-feeding: during oral treatment, breast-feeding should be avoided because corticosteroids are excreted in breast milk. By local route, the transdermal passage and therefore the risk of excretion of the corticosteroid in the milk will depend on the surface treated, the degree of epidermal damage and the duration of treatment.

TATE TO ASK FOR THE ADVICE OF YOUR DOCTOR OR YOUR PHARMACIST.

PREGNANCY & BREAST-FEEDING & FERTILITY

Pregnancy

  • No teratogenicity studies have been performed with topical corticosteroids.
  • However, studies concerning the intake of oral corticosteroids have not revealed a higher risk of malformation than that observed in the general population.

Breast-feeding

  • During oral treatment, breast-feeding should be avoided because corticosteroids are excreted in breast milk.

By local route, the transdermal passage and therefore the risk of excretion of the corticosteroid in the milk will depend on the surface treated, the degree of epidermal damage and the duration of treatment.

What happens if I overdose from Alkocortenbioform ?

If you use more ALKOCORTENBIOFORM, cream than you should:

  • Always use ALKOCORTENBIOFORM, cream as your doctor has told you.
  • Excessive or prolonged use of topical corticosteroids may be the cause of exacerbation of undesirable effects, and systemic passage is not excluded.
  • In case of systemic overdose, appropriate symptomatic treatment is indicated. If you have used more ALKOCORTENBIOFORM, cream than you need, contact your doctor.

What should I do if I miss a dose?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What happens if you stop taking Alkocortenbioform ?

  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.
  • Not applicable.

What is  Forms and Composition ?

Appearance and shape

  • Lack of information in the MA.
  • 15 g sealed aluminum tube coated internally with epoxyphenolic varnish and closed with a high density polyethylene stopper.

Composition

Active ingredient Cream
Flumetasone 0.02 g *
Clioquinol 3 g *

* per unit dose

Active ingredients: Flumetasone , Clioquinol

Excipients with known effects ?

  • Cetyl alcohol, Stearyl alcohol
Other excipients: Synthetic whale white, Vaseline, Glycerol, Sodium lauryl sulfate, Purified water

NOT’s

Edrug-online contains comprehensive and detailed information about drugs available in the medical field, and is divided into four sections:

general information:

Additional information:

  • General explanation about dealing with the medicine: how to take the medicine, the doses and times of it, the start and duration of its effectiveness, the recommended diet during the period of taking the medicine, the method of storage and storage, recommendations in cases for forgetting the dose and instructions to stop taking the drug and take additional doses.

Special warnings:

  • For pregnant and breastfeeding women, the elderly, boys and drivers, and use before surgery.

Side effects:

  • It treats possible side effects and drug interactions that require attention and its effect on continuous use.
  • The information contained in this medicine is based on medical literature, but it is not a substitute for consulting a doctor.
]]>
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